Gene Symbol | GDPD2 |
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Entrez Gene | 54857 |
Alt Symbol | GDE3, OBDPF |
Species | Human |
Gene Type | protein-coding |
Description | glycerophosphodiester phosphodiesterase domain containing 2 |
Other Description | glycerophosphodiester phosphodiesterase 3|glycerophosphodiester phosphodiesterase domain-containing protein 2|glycerophosphoinositol inositolphosphodiesterase GDPD2|osteoblast differentiation promoting factor |
Swissprots | B4DVC9 Q9HCC8 B4DRH4 Q9NXJ6 |
Accessions | EAX05339 EAX05340 Q9HCC8 AB048363 BAB13350 AI277430 AK000214 BAA91014 AK097293 BAG53448 AK299255 BAG61286 AK301025 BAG62641 AK307778 AK310090 AK316035 BAH14406 AY358986 AAQ89345 BC032009 AAH32009 DA934769 GQ129325 ACT64459 GQ129326 ACT64460 XM_011530977 XP_011529279 NM_001171191 NP_001164662 NM_001171192 NP_001164663 NM_001171193 NP_001164664 NM_017711 NP_060181 |
Function | Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with the actin cytoskeleton. {ECO:0000250}. |
GDE3 CRISPR/Cas9 KO Plasmid (h) - sc-412354 from Santa Cruz Biotechnology
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GDE3 HDR Plasmid (h) - sc-412354-HDR from Santa Cruz Biotechnology
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GDE3 Double Nickase Plasmid (h) - sc-412354-NIC from Santa Cruz Biotechnology
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GDE3 Double Nickase Plasmid (h2) - sc-412354-NIC-2 from Santa Cruz Biotechnology
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GDE3 CRISPR Activation Plasmid (h) - sc-412354-ACT from Santa Cruz Biotechnology
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GDE3 CRISPR Activation Plasmid (h2) - sc-412354-ACT-2 from Santa Cruz Biotechnology
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GDE3 Lentiviral Activation Particles (h) - sc-412354-LAC from Santa Cruz Biotechnology
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GDE3 Lentiviral Activation Particles (h2) - sc-412354-LAC-2 from Santa Cruz Biotechnology
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GDE3 siRNA (h) - sc-91305 from Santa Cruz Biotechnology
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GDE3 shRNA Plasmid (h) - sc-91305-SH from Santa Cruz Biotechnology
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GDE3 shRNA (h) Lentiviral Particles - sc-91305-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU084331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9223 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9223 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02128 from Sigma-Aldrich
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GDPD2 siRNA (Human) - CRJ0271 from Cohesion Biosciences
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GDPD2 - MBS8212071 from MyBioSource
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shRNA set against Human GDPD2 (NM_017711.3) - SHH300406 from Creative biogene
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Human GDPD2 siRNA - orb270772 from Biorbyt
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GDPD2 shRNA Plasmid (Human) - CHJ0271 from Cohesion Biosciences
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GDPD2 miRNA 3'UTR clone - MiUTR3H-14988 from Creative biogene
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