Gene Symbol | GDPD2 |
---|---|
Entrez Gene | 54857 |
Alt Symbol | GDE3, OBDPF |
Species | Human |
Gene Type | protein-coding |
Description | glycerophosphodiester phosphodiesterase domain containing 2 |
Other Description | glycerophosphodiester phosphodiesterase 3|glycerophosphodiester phosphodiesterase domain-containing protein 2|glycerophosphoinositol inositolphosphodiesterase GDPD2|osteoblast differentiation promoting factor |
Swissprots | B4DVC9 Q9HCC8 B4DRH4 Q9NXJ6 |
Accessions | EAX05339 EAX05340 Q9HCC8 AB048363 BAB13350 AI277430 AK000214 BAA91014 AK097293 BAG53448 AK299255 BAG61286 AK301025 BAG62641 AK307778 AK310090 AK316035 BAH14406 AY358986 AAQ89345 BC032009 AAH32009 DA934769 GQ129325 ACT64459 GQ129326 ACT64460 XM_011530977 XP_011529279 NM_001171191 NP_001164662 NM_001171192 NP_001164663 NM_001171193 NP_001164664 NM_017711 NP_060181 |
Function | Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with the actin cytoskeleton. {ECO:0000250}. |