| Gene Symbol |
UGCG
|
| Entrez Gene |
7357
|
| Alt Symbol |
GCS, GLCT1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP-glucose ceramide glucosyltransferase
|
| Other Description |
UDP-glucose:N-acylsphingosine D-glucosyltransferase|ceramide glucosyltransferase|glucosylceramide synthase
|
| Swissprots |
Q5T258 Q16739
|
| Accessions |
EAW59091 EAW59092 Q16739 AJ420423 AK314847 BAG37364 BC038711 AAH38711 BM052821 D50840 BAA09451 JF432523 ADZ15740 XM_005252186 XP_005252243 NM_003358 NP_003349
|
| Function |
Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase". {ECO:0000269|PubMed:8643456}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Found in all tissues examined. {ECO:0000269|PubMed:8643456}.
|
| Top Pathways |
Sphingolipid metabolism
|
![Western Blot: UGCG Overexpression Lysate (Adult Normal) [NBL1-17592] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UGCG.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26238_UGCG%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17592-img0002.jpg)