| Gene Symbol | UGCG |
|---|---|
| Entrez Gene | 7357 |
| Alt Symbol | GCS, GLCT1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP-glucose ceramide glucosyltransferase |
| Other Description | UDP-glucose:N-acylsphingosine D-glucosyltransferase|ceramide glucosyltransferase|glucosylceramide synthase |
| Swissprots | Q5T258 Q16739 |
| Accessions | EAW59091 EAW59092 Q16739 AJ420423 AK314847 BAG37364 BC038711 AAH38711 BM052821 D50840 BAA09451 JF432523 ADZ15740 XM_005252186 XP_005252243 NM_003358 NP_003349 |
| Function | Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase". {ECO:0000269|PubMed:8643456}. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Tissue Specificity | Found in all tissues examined. {ECO:0000269|PubMed:8643456}. |
| Top Pathways | Sphingolipid metabolism |