Gene Symbol | S100B |
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Entrez Gene | 525716 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | S100 calcium binding protein B |
Other Description | S-100 protein beta chain|S-100 protein subunit beta|S100 calcium-binding protein B|S100 protein, beta polypeptide|protein S100-B |
Swissprots | Q3ZBY1 A4IFR6 P02638 |
Accessions | DAA32950 P02638 BC103041 AAI03042 BC134727 AAI34728 DQ195377 ABA39829 NM_001034555 NP_001029727 |
Function | Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Nucleus. |
Tissue Specificity | Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues. |
S100 protein (Bovine) - 30R-AS044 from Fitzgerald
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Native Bovine S-100 Protein - S100B-256B from Creative Biomart
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Native Bovine S-100b Protein - S100B-257B from Creative Biomart
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Recombinant Bovine Protein S100-B(S100B) - CSB-YP020643BO CSB-EP020643BO CSB-BP020643BO CSB-MP020643BO from Cusabio
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S100B Recombinant Protein (OPCD06812) - OPCD06812 from Aviva Systems Biology
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Protein S100-B (S100B), Recombinant Protein - MBS963663 from MyBioSource
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