Gene Symbol | TAS2R38 |
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Entrez Gene | 5726 |
Alt Symbol | PTC, T2R38, T2R61 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 38 |
Other Description | PTC bitter taste receptor|taste receptor type 2 member 38|taste receptor type 2 member 61 |
Swissprots | A4D1U6 Q645W3 P59533 Q86UK3 Q2M3E8 P59552 |
Accessions | AAM19322 AAM63545 AAP14666 AAP14667 AFH77562 BAD98025 BAD98026 BAD98027 CAI53572 CAI53575 EAL24011 EAW83993 P59533 BC104933 AAI04934 BC104937 AAI04938 NM_176817 NP_789787 |
Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
Top Pathways | Taste transduction |
T2R38 (M-205) - sc-67109 from Santa Cruz Biotechnology
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T2R38 (H-220) - sc-67108 from Santa Cruz Biotechnology
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T2R38 (T-16) - sc-34294 from Santa Cruz Biotechnology
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Anti-TAS2R38 antibody - ab65509 from Abcam
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Anti-TAS2R38 antibody - ab130503 from Abcam
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Anti-TAS2R38 Antibody (aa305-332, AP) - LS-C241552 from LifeSpan Bioscience
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Anti-TAS2R38 Antibody (aa305-332, APC) - LS-C241553 from LifeSpan Bioscience
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Anti-TAS2R38 Antibody (aa305-332, FITC) - LS-C241555 from LifeSpan Bioscience
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Anti-TAS2R38 Antibody (aa305-332, Biotin) - LS-C241554 from LifeSpan Bioscience
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Anti-TAS2R38 Antibody (aa305-332, PE) - LS-C241556 from LifeSpan Bioscience
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Anti-TAS2R38 Antibody (aa305-332, Azide-free, HRP) - LS-C248310 from LifeSpan Bioscience
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Anti-TAS2R38 Antibody (aa304-332) - LS-C325579 from LifeSpan Bioscience
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Anti-TAS2R38 Antibody (aa305-332) - LS-C161713 from LifeSpan Bioscience
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TAS2R38 Antibody - NBP2-33711 from Novus Biologicals
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TAS2R38 Antibody - NBP2-33404 from Novus Biologicals
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TAS2R38 Antibody - NB110-74900 from Novus Biologicals
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T2R38 Polyclonal Antibody - bs-8650R from Bioss
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ANTI-TAS2R38 (C-TERM) antibody produced in rabbit - SAB1302680 from Sigma-Aldrich
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Anti-TAS2R38 antibody produced in rabbit - HPA054366 from Sigma-Aldrich
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TAS2R38-Antibody-C-term - AP16929b from Abgent, a WuXi AppTec company
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TAS2R38 Antibody - C-terminal region (OAAB12344) - OAAB12344 from Aviva Systems Biology
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TAS2R38 Antibody - abx029161 from Abbexa
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Anti-Patched 1 (PTCH1) - 20-5516 from ARP American Research Products
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TAS2R38, Polyclonal Antibody - MBS6003984 from MyBioSource
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PTCH1 Polyclonal Antibody - ESAP10715 from Elabscience
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