Gene Symbol | HIST1H2AG |
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Entrez Gene | 8969 |
Alt Symbol | H2A.1b, H2A/p, H2AFP, H2AG, pH2A/f |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2ag |
Other Description | H2A histone family, member P|H2A.1|histone 1, H2ag|histone H2A type 1|histone H2A/p |
Swissprots | P0C0S8 Q76PA6 Q2M1R2 |
Accessions | AAN59968 EAX03083 AK312124 BAG35060 BC016677 AAH16677 BC067782 DQ891024 ABM81950 DQ894204 ABM85130 DQ894286 ABM85212 L19778 AAC24466 NM_021064 NP_066408 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
Histone cluster 1 H2AG CRISPR/Cas9 KO Plasmid (h) - sc-411230 from Santa Cruz Biotechnology
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Histone cluster 1 H2AG HDR Plasmid (h) - sc-411230-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2AG Double Nickase Plasmid (h) - sc-411230-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2AG Double Nickase Plasmid (h2) - sc-411230-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AG CRISPR Activation Plasmid (h) - sc-411230-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2AG CRISPR Activation Plasmid (h2) - sc-411230-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AG Lentiviral Activation Particles (h) - sc-411230-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2AG Lentiviral Activation Particles (h2) - sc-411230-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2AG siRNA (h) - sc-105464 from Santa Cruz Biotechnology
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Histone cluster 1 H2AG shRNA Plasmid (h) - sc-105464-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2AG shRNA (h) Lentiviral Particles - sc-105464-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU020091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10061 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10497 from Sigma-Aldrich
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HIST1H2AG siRNA (Human) - CRH5919 from Cohesion Biosciences
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shRNA set against Human HIST1H2AG (NM_021064.4) - SHH312477 from Creative biogene
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HIST1H2AG shRNA Plasmid (Human) - CHH5919 from Cohesion Biosciences
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HIST1H2AG miRNA 3'UTR clone - MiUTR3H-15048 from Creative biogene
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