Gene Symbol |
HIST1H2AG
|
Entrez Gene |
8969
|
Alt Symbol |
H2A.1b, H2A/p, H2AFP, H2AG, pH2A/f
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
histone cluster 1, H2ag
|
Other Description |
H2A histone family, member P|H2A.1|histone 1, H2ag|histone H2A type 1|histone H2A/p
|
Swissprots |
P0C0S8 Q76PA6 Q2M1R2
|
Accessions |
AAN59968 EAX03083 AK312124 BAG35060 BC016677 AAH16677 BC067782 DQ891024 ABM81950 DQ894204 ABM85130 DQ894286 ABM85212 L19778 AAC24466 NM_021064 NP_066408
|
Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
Subcellular Location |
Nucleus. Chromosome.
|
Top Pathways |
Systemic lupus erythematosus, Alcoholism
|