Gene Symbol | TAF5 |
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Entrez Gene | 6877 |
Alt Symbol | TAF2D, TAFII100 |
Species | Human |
Gene Type | protein-coding |
Description | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
Other Description | TAF(II)100|TAFII-100|TATA box binding protein (TBP)-associated factor 2D|TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD|transcription initiation factor TFIID 100 kD subunit|transcription initiation factor TFIID 100 kDa subunit|transcription initiation factor TFIID subunit 5 |
Swissprots | Q5SYD5 Q9Y4K5 Q15542 Q53EM4 B7ZKJ6 B2RMR0 A8K5B4 Q86UZ7 |
Accessions | EAW49645 EAW49646 Q15542 AK223615 BAD97335 AK291229 BAF83918 AL137373 AW136916 BC052268 AAH52268 BC136340 AAI36341 BC136348 AAI36349 BG290312 U75309 AAC50902 U80191 AAC51215 X95525 CAA64777 XM_011540108 XP_011538410 NM_006951 NP_008882 |
Function | TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed. |
Subcellular Location | Nucleus. |
Top Pathways | Herpes simplex infection, Basal transcription factors |
TAF II p100 CRISPR/Cas9 KO Plasmid (h) - sc-407475 from Santa Cruz Biotechnology
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TAF II p100 HDR Plasmid (h) - sc-407475-HDR from Santa Cruz Biotechnology
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TAF II p100 Double Nickase Plasmid (h) - sc-407475-NIC from Santa Cruz Biotechnology
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TAF II p100 Double Nickase Plasmid (h2) - sc-407475-NIC-2 from Santa Cruz Biotechnology
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TAF II p100 CRISPR Activation Plasmid (h) - sc-407475-ACT from Santa Cruz Biotechnology
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TAF II p100 CRISPR Activation Plasmid (h2) - sc-407475-ACT-2 from Santa Cruz Biotechnology
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TAF II p100 Lentiviral Activation Particles (h) - sc-407475-LAC from Santa Cruz Biotechnology
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TAF II p100 Lentiviral Activation Particles (h2) - sc-407475-LAC-2 from Santa Cruz Biotechnology
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TAF II p100 siRNA (h) - sc-38498 from Santa Cruz Biotechnology
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TAF II p100 shRNA Plasmid (h) - sc-38498-SH from Santa Cruz Biotechnology
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TAF II p100 shRNA (h) Lentiviral Particles - sc-38498-V from Santa Cruz Biotechnology
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TAF5 RNAi - H00006877-R01 from Novus Biologicals
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MISSION® esiRNA - EHU133371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20974 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20974 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06673 from Sigma-Aldrich
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TAF5 siRNA (Human) - CRH4706 from Cohesion Biosciences
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TAF5 - MBS829959 from MyBioSource
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shRNA set against Human TAF5 (NM_006951.3) - SHH422740 from Creative biogene
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shRNA set against Human TAF5(NM_006951.3) - SHL054766 from Creative biogene
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Human TAF5 siRNA - orb265208 from Biorbyt
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TAF5 shRNA Plasmid (Human) - CHH4706 from Cohesion Biosciences
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TAF5 miRNA 3'UTR clone - MiUTR1H-10158 from Creative biogene
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