| Gene Symbol |
TAF5
|
| Entrez Gene |
6877
|
| Alt Symbol |
TAF2D, TAFII100
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
|
| Other Description |
TAF(II)100|TAFII-100|TATA box binding protein (TBP)-associated factor 2D|TATA box binding protein (TBP)-associated factor, RNA polymerase II, D, 100kD|transcription initiation factor TFIID 100 kD subunit|transcription initiation factor TFIID 100 kDa subunit|transcription initiation factor TFIID subunit 5
|
| Swissprots |
Q5SYD5 Q9Y4K5 Q15542 Q53EM4 B7ZKJ6 B2RMR0 A8K5B4 Q86UZ7
|
| Accessions |
EAW49645 EAW49646 Q15542 AK223615 BAD97335 AK291229 BAF83918 AL137373 AW136916 BC052268 AAH52268 BC136340 AAI36341 BC136348 AAI36349 BG290312 U75309 AAC50902 U80191 AAC51215 X95525 CAA64777 XM_011540108 XP_011538410 NM_006951 NP_008882
|
| Function |
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
Herpes simplex infection, Basal transcription factors
|