C1QA

Gene Symbol	C1QA
Entrez Gene	712
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	complement component 1, q subcomponent, A chain
Other Description	complement C1q subcomponent subunit A|complement component 1, q subcomponent, alpha polypeptide|complement component C1q, A chain
Swissprots	P02745 B2R4X2 Q5T963
Accessions	AAV40828 EAW95014 EAW95015 P02745 AF135157 AAD32626 AF260332 AAG44663 AK311980 BAG34919 BC030153 AAH30153 BC071986 AAH71986 BG548439 BX369252 EU832816 ACE87827 GQ129447 ACT64581 HQ447673 ADQ32158 NM_015991 NP_057075
Function	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

C1q-A CRISPR/Cas9 KO Plasmid (h) - sc-402156 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A HDR Plasmid (h) - sc-402156-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A Double Nickase Plasmid (h) - sc-402156-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A Double Nickase Plasmid (h2) - sc-402156-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A CRISPR Activation Plasmid (h) - sc-402156-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A CRISPR Activation Plasmid (h2) - sc-402156-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A Lentiviral Activation Particles (h) - sc-402156-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A Lentiviral Activation Particles (h2) - sc-402156-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A siRNA (h) - sc-43651 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

C1q-A shRNA Plasmid (h) - sc-43651-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

C1q-A shRNA (h) Lentiviral Particles - sc-43651-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU079631 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4682 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4682 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02699 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02699

C1QA siRNA (Human) - CRH0491 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

C1q RNAi - H00000712-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

C1QA - MBS8231212 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

C1q-A CRISPR/Cas9 KO Plasmid (h2) - sc-402156-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

C1q-A HDR Plasmid (h2) - sc-402156-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human C1QA (NM_015991.2) - SHH250673 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human C1QA(NM_015991.2) - SHG111295 from Creative biogene Category siRNA Species Reactivities Human

Human C1QA siRNA - orb260993 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

C1QA shRNA Plasmid (Human) - CHH0491 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

C1QA miRNA 3'UTR clone - MiUTR1H-01282 from Creative biogene Species Reactivities Human

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