Gene Symbol | C1QA |
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Entrez Gene | 712 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | complement component 1, q subcomponent, A chain |
Other Description | complement C1q subcomponent subunit A|complement component 1, q subcomponent, alpha polypeptide|complement component C1q, A chain |
Swissprots | P02745 B2R4X2 Q5T963 |
Accessions | AAV40828 EAW95014 EAW95015 P02745 AF135157 AAD32626 AF260332 AAG44663 AK311980 BAG34919 BC030153 AAH30153 BC071986 AAH71986 BG548439 BX369252 EU832816 ACE87827 GQ129447 ACT64581 HQ447673 ADQ32158 NM_015991 NP_057075 |
Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection |
C1QA-Over-expression-Lysate - LY11894a from Abgent, a WuXi AppTec company
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C1QA 293T Cell Transient Overexpression Lysate(Denatured) - H00000712-T01 from Acris Antibodies
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C1QA 293T Cell Transient Overexpression Lysate(Denatured) - H00000712-T02 from Acris Antibodies
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C1QA 293 Cell Lysate - 406866 from ABBIOTEC
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C1q Overexpression Lysate (Denatured) - H00000712-T02 from Novus Biologicals
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C1q Overexpression Lysate (Denatured) - H00000712-T01 from Novus Biologicals
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C1q Overexpression Lysate (Native) - NBL1-08337 from Novus Biologicals
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C1QA Over-expression Lysate Product - GWB-9A0D67 from Genway Biotech
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Human Complement C1q Deficient Plasma (EDTA) - D710104 from AssayPro
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Human Complement C1q Deficient Plasma (EDTA) - D710105 from AssayPro
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Human Complement C1q Deficient Plasma (EDTA) - D710106 from AssayPro
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Human Complement C1q Deficient Plasma (Heparin) - D710107 from AssayPro
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Human Complement C1q Deficient Plasma (Heparin) - D710108 from AssayPro
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Human Complement C1q Deficient Plasma (Heparin) - D710109 from AssayPro
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Human Complement C1q Deficient Plasma (Sodium Citrate) - D710101 from AssayPro
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Human Complement C1q Deficient Plasma (Sodium Citrate) - D710102 from AssayPro
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Human Complement C1q Deficient Plasma (Sodium Citrate) - D710103 from AssayPro
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Human Complement C1q Deficient Serum - D710110 from AssayPro
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Human Complement C1q Deficient Serum - D710111 from AssayPro
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Human Complement C1q Deficient Serum - D710112 from AssayPro
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C1q Overexpression Lysate (Denatured) - H00000712-T03 from Novus Biologicals
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Panoply™ Human C1QA Knockdown Stable Cell Line - CSC-DC001916 from Creative biogene
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