Gene Symbol | KSR1 |
---|---|
Entrez Gene | 8844 |
Alt Symbol | KSR, RSU2 |
Species | Human |
Gene Type | protein-coding |
Description | kinase suppressor of ras 1 |
Other Description | kinase suppressor of Ras 1 |
Swissprots | F8WEA9 Q13476 Q8IVT5 H7BYU0 |
Accessions | CAE84533 CAE84534 EAW51034 EAW51035 Q8IVT5 AK095721 AK124344 AK130719 BAC85413 BC035488 BC037586 BC042106 AAH42106 BC167812 AAI67812 BI829205 BX396814 U43586 AAC50354 XM_006722151 XP_006722214 XM_006722152 XP_006722215 XM_006722154 XP_006722217 XM_011525428 XP_011523730 XM_011525429 XP_011523731 XM_011525430 XP_011523732 XM_011525431 XP_011523733 XM_011525432 XP_011523734 XM_011525433 XP_011523735 XM_011525434 XP_011523736 XM_011525435 XP_011523737 XM_011525436 XP_011523738 XM_011525437 XP_011523739 XR_934587 XR_934588 XR_934589 NM_014238 NP_055053 |
Function | Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20679487}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:20679487}. Note=In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery (By similarity). {ECO:0000250}. |
Top Pathways | Tuberculosis |
Mouse/Human Phospho-KSR1 (Ser392) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1089 from LifeSpan Bioscience
|
||||||||||
Mouse/Human KSR1 ELISA Kit (Cell-Based ELISA) - LS-F2112 from LifeSpan Bioscience
|
||||||||||
Mouse KSR1 ELISA Kit (Sandwich ELISA) - LS-F11907 from LifeSpan Bioscience
|
||||||||||
Kinase suppressor of Ras 1, KSR1, Human, ELISA Kit - E14081h from ARP American Research Products
|
||||||||||
KSR Colorimetric Cell-Based ELISA Kit - CB5410 from Assay Biotechnology
|
||||||||||
KSR (Phospho-Ser392) Colorimetric Cell-Based ELISA Kit - CBP1068 from Assay Biotechnology
|
||||||||||
kinase suppressor of ras 1, ELISA Kit - MBS9325123 from MyBioSource
|
||||||||||
Human KSR1 ELISA Kit (Custom ELISA) - LS-F17145 from LifeSpan Bioscience
|
||||||||||
KSR ELISA Kit - DEIA-XYA1117 from Creative Diagnostics
|
||||||||||
KSR (Phospho-Ser392) ELISA Kit - DEIA-XYA1118 from Creative Diagnostics
|
||||||||||
Human KSR1 ELISA Kit - E021807 from Biobool
|
||||||||||
KSR1 ELISA Kit (Human) (OKEH05519) - OKEH05519 from Aviva Systems Biology
|
||||||||||
Kinase suppressor of Ras 1, ELISA Kit - MBS2885417 from MyBioSource
|
||||||||||
Kinase suppressor of Ras 1, ELISA Kit - MBS763073 from MyBioSource
|
||||||||||
Mouse KSR1 ELISA Kit (Sandwich ELISA) - LS-F35030 from LifeSpan Bioscience
|
||||||||||
KSR Colorimetric Cell-Based ELISA Kit - EKA50347 from Biomatik
|