| Gene Symbol |
HYOU1
|
| Entrez Gene |
10525
|
| Alt Symbol |
GRP-170, Grp170, HSP12A, ORP-150, ORP150
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hypoxia up-regulated 1
|
| Other Description |
150 kDa oxygen-regulated protein|170 kDa glucose-regulated protein|hypoxia up-regulated protein 1|oxygen regulated protein (150kD)
|
| Swissprots |
B7Z909 Q2I204 A8C1Z0 Q53H25 Q9Y4L1
|
| Accessions |
ACA06002 BAF80348 EAW67440 EAW67441 EAW67442 EAW67443 Q9Y4L1 AA580314 AK127324 BAG54482 AK222756 BAD96476 AK294905 BAH11920 AK297260 BAH12532 AK299648 BAH13088 AK301514 BAH13502 AK304264 BAH14145 AK307624 AK314178 BAG36860 BC004560 AAH04560 BC017726 AAH17726 BC072436 AAH72436 BE733065 BE791468 BP236985 BP358970 CR749610 CAH18405 DC364982 DQ350134 ABC75106 DQ372932 ABD14370 HY089857 U65785 AAC50947 XM_005271392 XP_005271449 XM_005271393 XP_005271450 XM_005271394 XP_005271451 XM_011542557 XP_011540859 XM_011542558 XP_011540860 XM_011548778 XP_011547080 XM_011548779 XP_011547081 XM_011548780 XP_011547082 XM_011548781 XP_011547083 XM_011548782 XP_011547084 XR_947790 XR_953214 NM_001130991 NP_001124463 NM_006389 NP_006380
|
| Function |
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding. {ECO:0000269|PubMed:10037731}.
|
| Subcellular Location |
Endoplasmic reticulum lumen.
|
| Tissue Specificity |
Highly expressed in tissues that contain well- developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|
