Gene Symbol | IL31 |
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Entrez Gene | 386653 |
Alt Symbol | IL-31 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 31 |
Other Description | interleukin-31 |
Swissprots | A2RUQ1 Q6EBC2 |
Accessions | CAL44872 CAL44939 CAL44950 CAL91842 CAP40193 CAT05434 CAV32859 CAX21673 CAX86999 CBL94048 CBX32717 CDM63719 EAW98310 Q6EBC2 AY499343 AAS86448 BC132998 AAI32999 BC133000 AAI33001 XM_011538326 XP_011536628 NM_001014336 NP_001014358 |
Function | Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. {ECO:0000269|PubMed:15184896}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. {ECO:0000269|PubMed:15184896}. |
IL-31 CRISPR/Cas9 KO Plasmid (h) - sc-410448 from Santa Cruz Biotechnology
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IL-31 HDR Plasmid (h) - sc-410448-HDR from Santa Cruz Biotechnology
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IL-31 Double Nickase Plasmid (h) - sc-410448-NIC from Santa Cruz Biotechnology
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IL-31 Double Nickase Plasmid (h2) - sc-410448-NIC-2 from Santa Cruz Biotechnology
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IL-31 CRISPR Activation Plasmid (h) - sc-410448-ACT from Santa Cruz Biotechnology
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IL-31 CRISPR Activation Plasmid (h2) - sc-410448-ACT-2 from Santa Cruz Biotechnology
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IL-31 Lentiviral Activation Particles (h) - sc-410448-LAC from Santa Cruz Biotechnology
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IL-31 Lentiviral Activation Particles (h2) - sc-410448-LAC-2 from Santa Cruz Biotechnology
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IL-31 siRNA (h) - sc-60838 from Santa Cruz Biotechnology
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IL-31 shRNA Plasmid (h) - sc-60838-SH from Santa Cruz Biotechnology
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IL-31 shRNA (h) Lentiviral Particles - sc-60838-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10627 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10627 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03566 from Sigma-Aldrich
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IL31 siRNA (Human) - CRJ7708 from Cohesion Biosciences
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IL31 - MBS8239136 from MyBioSource
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shRNA set against Human IL31 (NM_001014336.1) - SHH318897 from Creative biogene
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shRNA set against Human IL31(NM_001014336.1) - SHL175302 from Creative biogene
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Human IL31 siRNA - orb278209 from Biorbyt
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IL31 shRNA Plasmid (Human) - CHJ7708 from Cohesion Biosciences
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IL31 miRNA 3'UTR clone - MiUTR1H-04918 from Creative biogene
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