Gene Symbol | IL31 |
---|---|
Entrez Gene | 386653 |
Alt Symbol | IL-31 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 31 |
Other Description | interleukin-31 |
Swissprots | A2RUQ1 Q6EBC2 |
Accessions | CAL44872 CAL44939 CAL44950 CAL91842 CAP40193 CAT05434 CAV32859 CAX21673 CAX86999 CBL94048 CBX32717 CDM63719 EAW98310 Q6EBC2 AY499343 AAS86448 BC132998 AAI32999 BC133000 AAI33001 XM_011538326 XP_011536628 NM_001014336 NP_001014358 |
Function | Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. {ECO:0000269|PubMed:15184896}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. {ECO:0000269|PubMed:15184896}. |