DBT

Gene Symbol	DBT
Entrez Gene	1629
Alt Symbol	BCATE2, BCKAD-E2, BCKADE2, BCOADC-E2, E2, E2B
Species	Human
Gene Type	protein-coding
Description	dihydrolipoamide branched chain transacylase E2
Other Description	52 kDa mitochondrial autoantigen of primary biliary cirrhosis|BCKAD E2 subunit|E2 component of branched chain alpha-keto acid dehydrogenase complex|branched chain 2-oxo-acid dehydrogenase complex component E2|branched chain acyltransferase, E2 component|branched-chain alpha-keto acid dehydrogenase complex component E2|dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex|dihydrolipoyl transacylase|dihydrolipoyllysine-residue (2-methylpropanoyl)transferase|lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial|lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex|mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b)
Swissprots	B2R811 P11182 Q5VVL8
Accessions	CAA48225 EAW72963 P11182 AK024946 AK303941 BAG64869 AK313191 BAG36008 BC016675 AAH16675 BC030002 BT007372 AAP36036 DA274670 J03208 AAA35589 M19301 AAA59200 M27093 AAA64512 X57677 X66785 CAA47285 XM_005270545 XP_005270602 XM_005270546 XP_005270603 XR_946560 NM_001918 NP_001909
Function	The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.
Subcellular Location	Mitochondrion matrix.
Top Pathways	Valine, leucine and isoleucine degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rubella Virus E2 protein - ab43033 from Abcam Category Protein Prices $195.00 Sizes 200 µg Source E. coli

Human coronavirus SARS spike glycoprotein peptide - ab39844 from Abcam Category Peptide Species Coronavirus

Human SARS spike glycoprotein peptide - ab39847 from Abcam Category Peptide Species Human

Rubella Virus E2 protein fragment - ab107948 from Abcam Category Protein Source E. coli

SARS spike glycoprotein protein fragment - ab49043 from Abcam Category Protein Source E. coli

SARS spike glycoprotein protein fragment - ab49044 from Abcam Category Protein Source E. coli

SARS spike glycoprotein protein fragment - ab49046 from Abcam Category Protein Source E. coli

DBT / E2 Antibody Blocking Peptide - LS-E18663 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Estradiol Protein (OPMA04293) - OPMA04293 from Aviva Systems Biology Category Protein Prices $440.00 Sizes 1 ml

Human E2 protein - orb244765 from Biorbyt Category Protein Species Human

Human BCOADC-E2 protein - orb167966 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human E2 protein - orb244752 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human E2 protein - orb246114 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

DBT Blocking Peptide - 33R-6946 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Estradiol-BSA - 80-1066 from Fitzgerald Prices $295.00 Sizes 500 µg

Estradiol-OVA - 80-1067 from Fitzgerald Prices $315.00 Sizes 500 µg

HCVE2 protein (His tag) - 80R-3891 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Rubella virus E2 protein - 30-1281 from Fitzgerald Category Protein Prices $1,195.00 Sizes 1 mg Source E.coli

Rubella virus E2 protein - 30-1282 from Fitzgerald Category Protein Prices $1,195.00 Sizes 1 mg Source E.coli

E2 - P5119 from Acris Antibodies Category Protein Prices $580.00 Sizes 50 µg

DBT fusion protein - ag3101 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

BCOADC-E2 Human - ENPS-091 from NeoScientific Category Protein Prices $65.00, $169.00, $5,330.00 Sizes 2 µg, 10 µg, 1 mg Source Sf9 insect cells. Species Human

Recombinant Human BCOADC-E2 - BP000562-ENZ-084 from Syd Labs Category Protein Prices $160.00, $4,100.00 Sizes 10 µg, 1 mg Source Sf9 insect cells-derived. Species Human

BCOADC-E2 Human Protein - GWB-BSP138 from Genway Biotech Category Protein Prices $75.00, $165.00, $4,540.00 Sizes 2 μg, 10 μg, 1000 μg Source Sf9 insect cells. Species Human

BCOADC-E2 - JNV-049 from Reagent Proteins Category Protein Prices $364.00, $4,256.00 Sizes 10.00 µg, 1 mg Source Sf9 insect cells.

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