| Gene Symbol |
MPLKIP
|
| Entrez Gene |
136647
|
| Alt Symbol |
ABHS, C7orf11, ORF20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
M-phase specific PLK1 interacting protein
|
| Other Description |
M-phase-specific PLK1-interacting protein|Russell-Silver syndrome region|TTD non-photosensitive 1 protein
|
| Swissprots |
Q8TAP9
|
| Accessions |
EAL23999 EAW94134 Q8TAP9 AK290098 BAF82787 BC026265 AAH26265 BG501110 HQ447766 ADQ32251 NM_138701 NP_619646
|
| Function |
May play a role in maintenance of cell cycle integrity by regulating mitosis or cytokinesis. {ECO:0000269|PubMed:17310276}.
|
| Subcellular Location |
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=The subcellular location is regulated during cell cycle. During interphase located in the nucleus. During mitosis located at the centrosome and dispersed in the cytoplasm. During telophase located in the midbody. Colocalizes with PLK1 at the centrosome in M phase.
|
| Tissue Specificity |
Expressed at highest levels in liver and kidney; intermediate expression in skeletal muscle, pancreas, heart and placenta; low expression in brain and lung. Expressed in epidermis and hair follicles. {ECO:0000269|PubMed:11829489, ECO:0000269|PubMed:15645389}.
|