Gene Symbol | SYCN |
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Entrez Gene | 342898 |
Alt Symbol | INSSA1, SYL |
Species | Human |
Gene Type | protein-coding |
Description | syncollin |
Other Description | insulin synthesis associated 1|insulin synthesis-associated protein 1 |
Swissprots | Q0VAF6 |
Accessions | Q0VAF6 AK130951 BC039541 BC121075 AAI21076 BC121076 AAI21077 NM_001080468 NP_001073937 |
Function | Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Lumenal side {ECO:0000250}. Note=Localizes to zymogen granules. Associated with lipid rafts in a cholesterol-dependent manner. {ECO:0000250}. |
syncollin CRISPR/Cas9 KO Plasmid (h) - sc-406380 from Santa Cruz Biotechnology
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syncollin HDR Plasmid (h) - sc-406380-HDR from Santa Cruz Biotechnology
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syncollin Double Nickase Plasmid (h) - sc-406380-NIC from Santa Cruz Biotechnology
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syncollin Double Nickase Plasmid (h2) - sc-406380-NIC-2 from Santa Cruz Biotechnology
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syncollin CRISPR Activation Plasmid (h) - sc-406380-ACT from Santa Cruz Biotechnology
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syncollin CRISPR Activation Plasmid (h2) - sc-406380-ACT-2 from Santa Cruz Biotechnology
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syncollin Lentiviral Activation Particles (h) - sc-406380-LAC from Santa Cruz Biotechnology
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syncollin Lentiviral Activation Particles (h2) - sc-406380-LAC-2 from Santa Cruz Biotechnology
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syncollin siRNA (h) - sc-97291 from Santa Cruz Biotechnology
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syncollin shRNA Plasmid (h) - sc-97291-SH from Santa Cruz Biotechnology
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syncollin shRNA (h) Lentiviral Particles - sc-97291-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN20876 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20876 from Sigma-Aldrich
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SYCN siRNA (Human) - CRJ7408 from Cohesion Biosciences
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SYCN - MBS8205113 from MyBioSource
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shRNA set against Human Sycn (NM_001080468.2) - SHH421488 from Creative biogene
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Human SYCN siRNA - orb277909 from Biorbyt
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SYCN shRNA Plasmid (Human) - CHJ7408 from Cohesion Biosciences
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