Gene Symbol |
SYCN
|
Entrez Gene |
342898
|
Alt Symbol |
INSSA1, SYL
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
syncollin
|
Other Description |
insulin synthesis associated 1|insulin synthesis-associated protein 1
|
Swissprots |
Q0VAF6
|
Accessions |
Q0VAF6 AK130951 BC039541 BC121075 AAI21076 BC121076 AAI21077 NM_001080468 NP_001073937
|
Function |
Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Lumenal side {ECO:0000250}. Note=Localizes to zymogen granules. Associated with lipid rafts in a cholesterol-dependent manner. {ECO:0000250}.
|