| Gene Symbol |
NKAP
|
| Entrez Gene |
79576
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NFKB activating protein
|
| Other Description |
NF-kappa-B-activating protein|NF-kappaB activating protein
|
| Swissprots |
Q9H638 Q96BQ2 Q6IPW6 Q8N5F7
|
| Accessions |
EAW89838 Q8N5F7 AK026279 BAB15428 AK094446 AL832118 AY388958 AAQ90402 BC000940 BC012770 BC015354 AAH15354 BC016783 AAH16783 BC018968 AAH18968 BC032442 AAH32442 BC071686 AAH71686 HQ448222 ADQ32702 NM_024528 NP_078804
|
| Function |
Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter. {ECO:0000269|PubMed:14550261, ECO:0000269|PubMed:19409814}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:14550261}.
|