Dach2

Gene Symbol Dach2
Entrez Gene 93837
Alt Symbol 9430028N04Rik
Species Mouse
Gene Type protein-coding
Description dachshund 2 (Drosophila)
Other Description dachshund homolog 2
Swissprots Q925Q8 Q8BMA0
Accessions EDL33419 Q925Q8 AF257217 AAK39983 AK020442 AK033050 BAC28138 AK038687 AK041446 AK042401 AK045154 AK051529 BB175077 BC059233 AAH59233 GQ247884 ACT33313 XM_006528413 XP_006528476 XM_006528416 XP_006528479 XM_011247710 XP_011246012 XM_011247711 XP_011246013 XM_011247712 XP_011246014 XM_011247713 XP_011246015 XM_011247714 XP_011246016 XM_011247715 XP_011246017 XM_011247716 XP_011246018 XM_011247717 XP_011246019 NM_001142570 NP_001136042 NM_001289732 NP_001276661 NM_001289733 NP_001276662 NM_001289734 NP_001276663 NM_033605 NP_291083
Function Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression. Probably binds to DNA via its DACHbox-N domain. {ECO:0000269|PubMed:12112464, ECO:0000269|PubMed:12130660}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in embryo, and at lower levels in the newborn. {ECO:0000269|PubMed:11287190}.

Dachshund homolog 2 / DACH2 antibody, Internal - GTX88789 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-Dachshund homolog 2 / DACH2 antibody, Internal used in Western blot. GTX88789

Anti -DACH2 (Dachshund Homolog 2, Dach2, FLJ31391, MGC138545) - 151205 from USBiological Life Science

Host Goat
Clonality Polyclonal

Anti-DACH2 antibody - STJ71494 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

DACH2 Polyclonal Antibody - PA5-18897 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot staining of NIH/3T3 cell lysate using PA5-18897 at a concentration of 0.03 ug/ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.
ARG64479 anti-Dachshund homolog 2 / DACH2 antibody WB image Western Blot: NIH3T3 cell lysate (35 µg protein in RIPA buffer) stained with ARG64479 anti-Dachshund homolog 2 / DACH2 antibody at 0.03 µg/ml dilution.

DACH2 antibody - TA303341 from Acris Antibodies

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TA303341 (0.03µg/ml) staining of NIH3T3 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

DACH2 antibody - orb31300 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal

Anti-Dachshund homolog 2 / DACH2 Goat Antibody - EB08389 from ARP American Research Products

Prices $315.00
Sizes 100 µg
Clonality Polyclonal
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