| Gene Symbol | Hgf |
|---|---|
| Entrez Gene | 15234 |
| Alt Symbol | C230052L06Rik, HGF/SF, NK1, NK2, SF, SF/HGF |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | hepatocyte growth factor |
| Other Description | hepatopoietin-A|scatter factor |
| Swissprots | Q64007 Q08048 Q6LBE6 O55027 Q53WS5 Q61662 |
| Accessions | CAA57286 EDL03238 EDL03239 EDL03240 Q08048 AF042856 AAC40051 AK033274 AK042121 BAC31175 AK052289 AK082461 BAC38497 AK142159 AK164241 BC119228 AAI19229 BC144764 D10212 BAA01064 D10213 BAA01065 S71816 AAB31855 X72307 CAA51054 X84046 CAA58865 XM_006535628 XP_006535691 XM_011249748 XP_011248050 NM_001289458 NP_001276387 NM_001289459 NP_001276388 NM_001289460 NP_001276389 NM_001289461 NP_001276390 NM_010427 NP_034557 |
| Function | Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. {ECO:0000269|PubMed:20624990}. |
| Top Pathways | Malaria, Proteoglycans in cancer, Rap1 signaling pathway, PI3K-Akt signaling pathway, Cytokine-cytokine receptor interaction |
HGFα/β siRNA (m) - sc-37112 from Santa Cruz Biotechnology
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HGFα/β shRNA Plasmid (m) - sc-37112-SH from Santa Cruz Biotechnology
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HGFα/β shRNA (m) Lentiviral Particles - sc-37112-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU037921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33211 from Sigma-Aldrich
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HGF siRNA (Mouse) - CRM1822 from Cohesion Biosciences
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HGF - MBS8217375 from MyBioSource
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shRNA set against Mouse Hgf (NM_010427.4) - SHH311913 from Creative biogene
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Mouse HGF siRNA - orb281298 from Biorbyt
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HGF shRNA Plasmid (Mouse) - CHM1822 from Cohesion Biosciences
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