| Gene Symbol |
Hgf
|
| Entrez Gene |
15234
|
| Alt Symbol |
C230052L06Rik, HGF/SF, NK1, NK2, SF, SF/HGF
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
hepatocyte growth factor
|
| Other Description |
hepatopoietin-A|scatter factor
|
| Swissprots |
Q64007 Q08048 Q6LBE6 O55027 Q53WS5 Q61662
|
| Accessions |
CAA57286 EDL03238 EDL03239 EDL03240 Q08048 AF042856 AAC40051 AK033274 AK042121 BAC31175 AK052289 AK082461 BAC38497 AK142159 AK164241 BC119228 AAI19229 BC144764 D10212 BAA01064 D10213 BAA01065 S71816 AAB31855 X72307 CAA51054 X84046 CAA58865 XM_006535628 XP_006535691 XM_011249748 XP_011248050 NM_001289458 NP_001276387 NM_001289459 NP_001276388 NM_001289460 NP_001276389 NM_001289461 NP_001276390 NM_010427 NP_034557
|
| Function |
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. {ECO:0000269|PubMed:20624990}.
|
| Top Pathways |
Malaria, Proteoglycans in cancer, Rap1 signaling pathway, PI3K-Akt signaling pathway, Cytokine-cytokine receptor interaction
|
