Gene Symbol | UBE2E1 |
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Entrez Gene | 7324 |
Alt Symbol | UBCH6 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2E 1 |
Other Description | ubiquitin carrier protein E1|ubiquitin-conjugating enzyme E2 E1|ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)|ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5)|ubiquitin-protein ligase E1 |
Swissprots | K4DI90 P51965 C9J8K2 B2RBX4 |
Accessions | EAW64329 EAW64330 EAW64331 EAW64332 EAW64333 P51965 AK295354 BAH12042 AK314854 BAG37371 BC009139 AAH09139 BF698653 BI223271 DB478686 DB499676 X92963 CAA63539 XM_005265431 XP_005265488 NM_001202476 NP_001189405 NM_003341 NP_003332 NM_182666 NP_872607 |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination. {ECO:0000269|PubMed:16428300, ECO:0000269|PubMed:20061386}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18845142}. |
Top Pathways | Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum |
Human UBCH6/UBE2E1 full length protein - ab131681 from Abcam
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UBE2E1 / UBCH6 Antibody Blocking Peptide - LS-E15999 from LifeSpan Bioscience
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UBE2E1 / UBCH6 Antibody Blocking Peptide - LS-E15829 from LifeSpan Bioscience
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UbcH6/UBE2E1 Recombinant Protein - H00007324-P01 from Novus Biologicals
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Recombinant Human UbcH6/UBE2E1 Protein - NBP2-22924 from Novus Biologicals
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Recombinant Human His6-UbcH6/UBE2E1, CF - E2-630-050 from R&D Systems
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Recombinant Human His6-UbcH6/UBE2E1, CF - E2-630-100 from R&D Systems
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Human UBE2E1 protein - orb169506 from Biorbyt
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Human UBE2E1 protein - orb139839 from Biorbyt
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UBE2E1 Blocking Peptide - 33R-7168 from Fitzgerald
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UBE2E1 protein (His tag) - 80R-2434 from Fitzgerald
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UBE2E1 (1-193, His-tag) - AR50514PU-N from Acris Antibodies
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UBE2E1 (1-193, His-tag) - AR50514PU-S from Acris Antibodies
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UBE2E1 - H00007324-P01-10 from Acris Antibodies
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UBE2E1 - H00007324-P01-25 from Acris Antibodies
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UBE2E1, 1-193aa, Human, His tag, E.coli - 01-P1690 from ARP American Research Products
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UBE2E1 Human - ENPS-654 from NeoScientific
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Recombinant UBCH6 protein - 31362 from ActiveMotif
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UbcH6 (UBE2E1) Active Human Recombinant Protein - GWB-2B4BDF from Genway Biotech
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Recombinant Human UBE2E1, None tagged - UBE2E1-852H from Creative Biomart
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UBE2E1 - PAT-80580-2 from Nordic BioSite
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UBE2E1 - PAT-80580-1 from Nordic BioSite
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UbcH6 Conjugating Enzyme, 100 µg - 14-812 from EMD Millipore
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UbcH6 Protein, active - 23-036-K from EMD Millipore
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Recombinant Human Ubiquitin-conjugating enzyme E2 E1(UBE2E1) - CSB-YP025448HU CSB-EP025448HU CSB-BP025448HU CSB-MP025448HU from Cusabio
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