Gene Symbol | UBE2E1 |
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Entrez Gene | 7324 |
Alt Symbol | UBCH6 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2E 1 |
Other Description | ubiquitin carrier protein E1|ubiquitin-conjugating enzyme E2 E1|ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)|ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5)|ubiquitin-protein ligase E1 |
Swissprots | K4DI90 P51965 C9J8K2 B2RBX4 |
Accessions | EAW64329 EAW64330 EAW64331 EAW64332 EAW64333 P51965 AK295354 BAH12042 AK314854 BAG37371 BC009139 AAH09139 BF698653 BI223271 DB478686 DB499676 X92963 CAA63539 XM_005265431 XP_005265488 NM_001202476 NP_001189405 NM_003341 NP_003332 NM_182666 NP_872607 |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination. {ECO:0000269|PubMed:16428300, ECO:0000269|PubMed:20061386}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18845142}. |
Top Pathways | Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum |
UBE2E1 (C-18) - sc-47547 from Santa Cruz Biotechnology
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UBE2E1 (N-13) - sc-47548 from Santa Cruz Biotechnology
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UBE2E1 (42) - sc-136113 from Santa Cruz Biotechnology
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Anti-UBCH6/UBE2E1 antibody - ab36980 from Abcam
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Anti-UBCH6/UBE2E1 antibody - ab90066 from Abcam
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Anti-UBE2E1 / UBCH6 Antibody (Biotin) - LS-C180961 from LifeSpan Bioscience
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Anti-UBE2E1 / UBCH6 Antibody (DY650) - LS-C180962 from LifeSpan Bioscience
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Anti-UBE2E1 / UBCH6 Antibody (DY488) - LS-C180963 from LifeSpan Bioscience
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Anti-UBE2E1 / UBCH6 Antibody (HRP) - LS-C180964 from LifeSpan Bioscience
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Anti-UBE2E1 / UBCH6 Antibody (DY550) - LS-C180965 from LifeSpan Bioscience
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Anti-UBE2E1 / UBCH6 Antibody (aa25-74) - LS-C151233 from LifeSpan Bioscience
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Anti-UBE2E1 / UBCH6 Antibody (aa71-120) - LS-C110743 from LifeSpan Bioscience
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Anti-UBE2E1 / UBCH6 Antibody - LS-C180183 from LifeSpan Bioscience
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UbcH6/UBE2E1 Antibody - NBP1-78983 from Novus Biologicals
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UbcH6/UBE2E1 Antibody - A-630 from Novus Biologicals
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UbcH6/UBE2E1 Antibody - NBP1-86886 from Novus Biologicals
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UbcH6/UBE2E1 Antibody [DyLight 550] - NBP1-78983R from Novus Biologicals
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UbcH6/UBE2E1 Antibody [HRP] - NBP1-78983H from Novus Biologicals
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UbcH6/UBE2E1 Antibody [DyLight 488] - NBP1-78983G from Novus Biologicals
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UbcH6/UBE2E1 Antibody [DyLight 650] - NBP1-78983C from Novus Biologicals
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UbcH6/UBE2E1 Antibody [Biotin] - NBP1-78983B from Novus Biologicals
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UbcH6/UBE2E1 Antibody [Alexa Fluor (R) 700] - NBP1-78983AF700 from Novus Biologicals
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UbcH6/UBE2E1 Antibody [Alexa Fluor (R) 647] - NBP1-78983AF647 from Novus Biologicals
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UbcH6/UBE2E1 Antibody [Alexa Fluor (R) 488] - NBP1-78983AF488 from Novus Biologicals
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UbcH6/UBE2E1 Antibody [Alexa Fluor (R) 405] - NBP1-78983AF405 from Novus Biologicals
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