Gene Symbol | Ifng |
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Entrez Gene | 15978 |
Alt Symbol | IFN-g, Ifg |
Species | Mouse |
Gene Type | protein-coding |
Description | interferon gamma |
Other Description | IFN-gamma|gamma interferon |
Swissprots | Q542B8 P01580 |
Accessions | EDL24379 P01580 AK089574 BAC40926 AY423847 AAR00339 BC119063 AAI19064 BC119065 AAI19066 EF423643 ABN80441 FJ617514 ACR22509 FJ617515 ACR22510 FJ617516 ACR22511 K00083 AAA37894 M28621 NM_008337 NP_032363 |
Function | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
Subcellular Location | Secreted. |
Tissue Specificity | Released primarily from activated T lymphocytes. |
Top Pathways | TGF-beta signaling pathway, Epstein-Barr virus infection, Herpes simplex infection, Tuberculosis, Inflammatory bowel disease (IBD) |
IFN-γ CRISPR/Cas9 KO Plasmid (m) - sc-421050 from Santa Cruz Biotechnology
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IFN-γ HDR Plasmid (m) - sc-421050-HDR from Santa Cruz Biotechnology
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IFN-γ Double Nickase Plasmid (m) - sc-421050-NIC from Santa Cruz Biotechnology
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IFN-γ Double Nickase Plasmid (m2) - sc-421050-NIC-2 from Santa Cruz Biotechnology
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IFN-γ CRISPR Activation Plasmid (m) - sc-421050-ACT from Santa Cruz Biotechnology
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IFN-γ CRISPR Activation Plasmid (m2) - sc-421050-ACT-2 from Santa Cruz Biotechnology
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IFN-γ Lentiviral Activation Particles (m) - sc-421050-LAC from Santa Cruz Biotechnology
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IFN-γ Lentiviral Activation Particles (m2) - sc-421050-LAC-2 from Santa Cruz Biotechnology
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IFN-γ siRNA (m) - sc-39607 from Santa Cruz Biotechnology
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IFN-γ shRNA Plasmid (m) - sc-39607-SH from Santa Cruz Biotechnology
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IFN-γ shRNA (m) Lentiviral Particles - sc-39607-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN33658 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33658 from Sigma-Aldrich
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IFNG siRNA (Mouse) - CRM2007 from Cohesion Biosciences
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IFNG - MBS8217322 from MyBioSource
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shRNA set against Mouse IFNG (NM_008337.3) - SHH317169 from Creative biogene
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shRNA set against Mouse Ifng(NM_008337.3) - SHL166738 from Creative biogene
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Mouse IFNG siRNA - orb281483 from Biorbyt
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IFNG shRNA Plasmid (Mouse) - CHM2007 from Cohesion Biosciences
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IFNG miRNA 3'UTR clone - MiUTR1M-05923 from Creative biogene
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