| Gene Symbol | Ifng |
|---|---|
| Entrez Gene | 15978 |
| Alt Symbol | IFN-g, Ifg |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | interferon gamma |
| Other Description | IFN-gamma|gamma interferon |
| Swissprots | Q542B8 P01580 |
| Accessions | EDL24379 P01580 AK089574 BAC40926 AY423847 AAR00339 BC119063 AAI19064 BC119065 AAI19066 EF423643 ABN80441 FJ617514 ACR22509 FJ617515 ACR22510 FJ617516 ACR22511 K00083 AAA37894 M28621 NM_008337 NP_032363 |
| Function | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Released primarily from activated T lymphocytes. |
| Top Pathways | TGF-beta signaling pathway, Epstein-Barr virus infection, Herpes simplex infection, Tuberculosis, Inflammatory bowel disease (IBD) |