Gene Symbol | CX3CR1 |
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Entrez Gene | 1524 |
Alt Symbol | CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X3-C motif) receptor 1 |
Other Description | C-X3-C CKR-1|CMK-BRL-1|CMK-BRL1|CX3C chemokine receptor 1|G protein-coupled receptor 13|G-protein coupled receptor 13|beta chemokine receptor-like 1|chemokine (C-C) receptor-like 1|chemokine (C-X3-C) receptor 1|fractalkine receptor |
Swissprots | P49238 J3KP17 B2R5Z4 A0N0N6 |
Accessions | AAK08627 ABK41927 ABS29268 EAW64575 EAW64576 P49238 AI400350 AK225764 AK307911 AK312373 BAG35291 BC017855 BC028078 AAH28078 BG541473 DA396634 DA406242 DB274136 DQ891063 ABM81989 DQ894243 ABM85169 U20350 AAA91783 U28934 AAA87032 NM_001171171 NP_001164642 NM_001171172 NP_001164643 NM_001171174 NP_001164645 NM_001337 NP_001328 |
Function | Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in lymphoid and neural tissues. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
Human-CX3CR1-cDNA-Clone - DC05761 from Abgent, a WuXi AppTec company
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Human CX3CR1 (NP_001328) VersaClone cDNA - RDC0042 from R&D Systems
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Mouse CX3CR1 (NP_034117) VersaClone cDNA - RDC0043 from R&D Systems
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Rat CX3CR1 (NP_598218) VersaClone cDNA - RDC0417 from R&D Systems
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CX3CR1 cDNA (ANA10189) - ANA10189 from Aviva Systems Biology
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CX3CR1 cDNA (ANA10190) - ANA10190 from Aviva Systems Biology
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CX3CR1 - MBS1270108 from MyBioSource
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Human CX3CR1 cDNA clone(NM_001171172.1) - CDFH004540 from Creative Biomart
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Human CX3CR1 cDNA clone(NM_001171171.1) - CDFH004541 from Creative Biomart
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Human CX3CR1 cDNA clone(NM_001171174.1) - CDFH004542 from Creative Biomart
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Human CX3CR1 cDNA clone(NM_001337.3) - CDFH004543 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001337.3) - CDCL160163 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001337.3) - CDCR280567 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001337.3) - CDCR280568 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001337.3) - CDCR280569 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001171171.1) - CDCR356213 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001171171.1) - CDCR356214 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001171172.1) - CDCR356215 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001171172.1) - CDCR356217 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001171174.1) - CDCR356218 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001171174.1) - CDCR356219 from Creative Biomart
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Human CX3CR1 ORF Clone(NM_001337.3) - CDCR280567 from Creative biogene
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Human CX3CR1 ORF Clone(NM_001171171.1) - CDCR356214 from Creative biogene
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Human CX3CR1 ORF Clone(NM_001171172.1) - CDCR356217 from Creative biogene
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Human CX3CR1 ORF clone (NM_001171174.1) - CDCR043752 from Creative biogene
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