Gene Symbol | B3GALTL |
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Entrez Gene | 145173 |
Alt Symbol | B3GLCT, B3GTL, B3Glc-T, Gal-T, beta3Glc-T |
Species | Human |
Gene Type | protein-coding |
Description | beta 1,3-galactosyltransferase-like |
Other Description | UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like|beta 3-glycosyltransferase-like|beta-1,3-glucosyltransferase|beta-3-glycosyltransferase-like |
Swissprots | A8K5F8 Q6Y288 Q6NUI3 Q5W0H2 |
Accessions | EAX08483 Q6Y288 AA769548 AB101481 BAD13528 AK094979 AK291273 BAF83962 AV728071 AY190526 AAO37647 BC031597 BC032021 BC047395 BC068595 AAH68595 BX647932 DA290408 DN999521 XM_006719768 XP_006719831 XM_011534936 XP_011533238 XM_011534937 XP_011533239 XM_011534938 XP_011533240 XR_941500 XR_941501 NM_194318 NP_919299 |
Function | O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. {ECO:0000269|PubMed:16899492}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:16899492}; Single-pass type II membrane protein {ECO:0000269|PubMed:16899492}. |
Tissue Specificity | Widely expressed, with highest levels in testis and uterus. {ECO:0000269|PubMed:12943678, ECO:0000269|PubMed:16899492}. |
Top Pathways | Other types of O-glycan biosynthesis |
β-1,3-Gal-TL siRNA (h) - sc-62006 from Santa Cruz Biotechnology
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β-1,3-Gal-TL shRNA Plasmid (h) - sc-62006-SH from Santa Cruz Biotechnology
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β-1,3-Gal-TL shRNA (h) Lentiviral Particles - sc-62006-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU008841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3801 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11642 from Sigma-Aldrich
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B3GALTL siRNA (Human) - CRJ5423 from Cohesion Biosciences
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B3GALTL - MBS8214186 from MyBioSource
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shRNA set against Human B3GALTL (NM_194318.3) - SHH244182 from Creative biogene
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shRNA set against Human B3GALTL(NM_194318.3) - SHG088553 from Creative biogene
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Human B3GALTL siRNA - orb275924 from Biorbyt
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B3GALTL shRNA Plasmid (Human) - CHJ5423 from Cohesion Biosciences
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B3GALTL miRNA 3'UTR clone - MiUTR1H-00765 from Creative biogene
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