| Gene Symbol |
B3GALTL
|
| Entrez Gene |
145173
|
| Alt Symbol |
B3GLCT, B3GTL, B3Glc-T, Gal-T, beta3Glc-T
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
beta 1,3-galactosyltransferase-like
|
| Other Description |
UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like|beta 3-glycosyltransferase-like|beta-1,3-glucosyltransferase|beta-3-glycosyltransferase-like
|
| Swissprots |
A8K5F8 Q6Y288 Q6NUI3 Q5W0H2
|
| Accessions |
EAX08483 Q6Y288 AA769548 AB101481 BAD13528 AK094979 AK291273 BAF83962 AV728071 AY190526 AAO37647 BC031597 BC032021 BC047395 BC068595 AAH68595 BX647932 DA290408 DN999521 XM_006719768 XP_006719831 XM_011534936 XP_011533238 XM_011534937 XP_011533239 XM_011534938 XP_011533240 XR_941500 XR_941501 NM_194318 NP_919299
|
| Function |
O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. {ECO:0000269|PubMed:16899492}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:16899492}; Single-pass type II membrane protein {ECO:0000269|PubMed:16899492}.
|
| Tissue Specificity |
Widely expressed, with highest levels in testis and uterus. {ECO:0000269|PubMed:12943678, ECO:0000269|PubMed:16899492}.
|
| Top Pathways |
Other types of O-glycan biosynthesis
|