USP1

Gene Symbol USP1
Entrez Gene 7398
Alt Symbol UBP
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 1
Other Description deubiquitinating enzyme 1|hUBP|ubiquitin carboxyl terminal hydrolase 1|ubiquitin carboxyl-terminal hydrolase 1|ubiquitin specific processing protease 1|ubiquitin specific protease 1|ubiquitin thioesterase 1|ubiquitin thiolesterase 1|ubiquitin-specific-processing protease 1
Swissprots A0PJ95 Q05BX7 Q9UFR0 Q59H66 D3DQ57 O94782 Q9UNJ3
Accessions EAX06585 EAX06586 O94782 AB014458 BAA34703 AB208893 BAD92130 AF117386 AAD11441 AK096788 AK312423 BAG35333 AL117503 CAB55967 AL117575 CAB55999 AL599240 AM392756 CAL37634 BC011881 BC018745 AAH18745 BC023216 BC032364 AAH32364 BC040140 BC050525 AAH50525 BI463072 BQ018843 BQ186837 NM_001017415 NP_001017415 NM_001017416 NP_001017416 NM_003368 NP_003359
Function Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. {ECO:0000269|PubMed:15694335, ECO:0000269|PubMed:16531995, ECO:0000269|PubMed:18082604}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15694335}.
Top Pathways Fanconi anemia pathway

USP1 (D37B4) Rabbit mAb - 8033 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D37B4
Western blot analysis of extracts from HeLa, A20 and COS cells using USP1 (D37B4) Rabbit mAb.

USP1 (C-14) - sc-104734 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP1 (C-14): sc-104734. Western blot analysis of USP1 expression in non-transfected: sc-117752 (A) and human USP1 transfected: sc-158057 (B) 293T whole cell lysates.

USP1 (E-14) - sc-104735 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

USP1 (H-300) - sc-135222 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
USP1 (H-300): sc-135222. Western blot analysis of USP1 expression in mouse brain tissue extract.

Anti-USP1 antibody - ab27868 from Abcam

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HEK293T cells, staining USP1 with ab27868 at 1/200 dilution.

Anti-USP1 antibody - ab108104 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-USP1 antibody - ab84772 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Staining of USP1 by Immunohistochemistry on a formalin fixed, paraffin embedded section of human thyroid carcinoma using a 1/250 dilution of ab84772. Detection: DAB staining

Anti-USP1 Antibody (N-Terminus, APC) - LS-C246331 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (aa661-690, AP) - LS-C242478 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (aa661-690, Biotin) - LS-C242479 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (aa661-690, APC) - LS-C242477 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (aa661-690, FITC) - LS-C242480 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (C-Terminus, AP) - LS-C246326 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (aa661-690, PE) - LS-C242483 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (C-Terminus, APC) - LS-C246327 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (C-Terminus, Biotin) - LS-C246328 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (C-Terminus, FITC) - LS-C246329 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (N-Terminus, AP) - LS-C246330 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (C-Terminus, PE) - LS-C246332 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (N-Terminus, Biotin) - LS-C246333 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (N-Terminus, FITC) - LS-C246334 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (N-Terminus, PE) - LS-C246338 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (aa661-690, Azide-free, HRP) - LS-C247200 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (C-Terminus, Azide-free, HRP) - LS-C247962 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP1 Antibody (N-Terminus, Azide-free, HRP) - LS-C247963 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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