SPAG5

Gene Symbol SPAG5
Entrez Gene 10615
Alt Symbol DEEPEST, MAP126, hMAP126
Species Human
Gene Type protein-coding
Description sperm associated antigen 5
Other Description astrin|mitotic spindle associated protein p126|mitotic spindle coiled-coil related protein|mitotic spindle-associated protein p126|sperm-associated antigen 5
Swissprots Q9UFE6 Q96R06 Q9BWE8 O95213 Q9NT17
Accessions EAW51106 Q96R06 AF063308 AAD02813 AF345347 AAL06396 AF399910 AAK91712 AK025725 AK292398 BAF85087 AL122116 CAB59275 AL137585 CAB70827 BC000322 AAH00322 BC113055 AAI13056 BI459711 BQ773438 NM_006461 NP_006452
Function Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule- kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation- induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU. {ECO:0000269|PubMed:11724960, ECO:0000269|PubMed:12356910, ECO:0000269|PubMed:17664331, ECO:0000269|PubMed:18055457, ECO:0000269|PubMed:21402792, ECO:0000269|Pu
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Chromosome, centromere, kinetochore. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic granule. Note=In a punctate pattern in interphase cells. During mitosis, detected at spindle poles during prophase, throughout the spindle in metaphase and anaphase, and at midzone microtubules in anaphase and telophase. Efficient targeting to the mitotic spindle may depend upon phosphorylation by GSK3B. Detected on kinetochores of chromosomes that have congressed. The astrin (SPAG5)-kinastrin (SKAP) complex localizes to the microtubule plus ends (By similarity). In non-mitotic non-stressed cells, shows a microtubuli pattern. In arsenite-stressed cells, accumulates in stress granules. {ECO:0000250}.
Tissue Specificity Highly expressed in testis. Detected at low levels in placenta, liver, pancreas, thymus and colon. {ECO:0000269|PubMed:11549262}.

sperm associated antigen 5, ELISA Kit - MBS9342448 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/ml.
Range 0.625 ng/ml - 20 ng/ml.

Human SPAG5 ELISA Kit - E098513 from Biobool

Category ELISA Kit

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9356161 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9357306 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9343536 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9346894 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9361088 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9364538 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9347143 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9358095 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9345828 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9365440 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9348869 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9362919 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9345266 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9351228 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SPAG5 (sperm associated antigen 5), ELISA Kit - MBS7606093 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/ml
Range 0.156-10ng/ml

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9365546 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9353453 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9374985 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9351838 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9349412 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9353656 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Sperm-Associated Antigen 5 (SPA5), ELISA Kit - MBS9352688 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SPAG5 ELISA Kit (Human) (OKWB00200) - OKWB00200 from Aviva Systems Biology

Category ELISA Kit
Sensitivity 0.094 ng/mL
Range 0.156 - 10 ng/mL
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