| Gene Symbol |
CACUL1
|
| Entrez Gene |
143384
|
| Alt Symbol |
C10orf46, CAC1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CDK2-associated, cullin domain 1
|
| Other Description |
CDK2-associated and cullin domain-containing protein 1|Cdk-Associated Cullin1|cullin
|
| Swissprots |
Q8IY11 Q86Y37 Q8N7S4 Q5XPL7
|
| Accessions |
EAW49411 EAW49412 Q86Y37 AJ544771 CAD67614 AK026985 AK057742 AK097728 BAC05153 AK131008 AK301182 BAG62766 AY743663 AAU89709 BC017894 BC038294 AAH38294 BG772719 BU623607 LK938920 XM_011539348 XP_011537650 XR_945608 NM_153810 NP_722517
|
| Function |
Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. {ECO:0000269|PubMed:19829063}.
|
| Tissue Specificity |
Ubiquitously expressed with highest expression in the mammary gland and large intestine. Highly expressed in cancer tissues and cancer cell lines. During cell cycle progression expression is high in G1/S, low in the middle of S phase, and increases again in S/G2 phase. {ECO:0000269|PubMed:19829063}.
|