Gene Symbol | CACUL1 |
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Entrez Gene | 143384 |
Alt Symbol | C10orf46, CAC1 |
Species | Human |
Gene Type | protein-coding |
Description | CDK2-associated, cullin domain 1 |
Other Description | CDK2-associated and cullin domain-containing protein 1|Cdk-Associated Cullin1|cullin |
Swissprots | Q8IY11 Q86Y37 Q8N7S4 Q5XPL7 |
Accessions | EAW49411 EAW49412 Q86Y37 AJ544771 CAD67614 AK026985 AK057742 AK097728 BAC05153 AK131008 AK301182 BAG62766 AY743663 AAU89709 BC017894 BC038294 AAH38294 BG772719 BU623607 LK938920 XM_011539348 XP_011537650 XR_945608 NM_153810 NP_722517 |
Function | Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. {ECO:0000269|PubMed:19829063}. |
Tissue Specificity | Ubiquitously expressed with highest expression in the mammary gland and large intestine. Highly expressed in cancer tissues and cancer cell lines. During cell cycle progression expression is high in G1/S, low in the middle of S phase, and increases again in S/G2 phase. {ECO:0000269|PubMed:19829063}. |
C10orf46 CRISPR/Cas9 KO Plasmid (h) - sc-414517 from Santa Cruz Biotechnology
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C10orf46 HDR Plasmid (h) - sc-414517-HDR from Santa Cruz Biotechnology
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C10orf46 Double Nickase Plasmid (h) - sc-414517-NIC from Santa Cruz Biotechnology
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C10orf46 Double Nickase Plasmid (h2) - sc-414517-NIC-2 from Santa Cruz Biotechnology
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C10orf46 CRISPR Activation Plasmid (h) - sc-414517-ACT from Santa Cruz Biotechnology
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C10orf46 CRISPR Activation Plasmid (h2) - sc-414517-ACT-2 from Santa Cruz Biotechnology
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C10orf46 Lentiviral Activation Particles (h) - sc-414517-LAC from Santa Cruz Biotechnology
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C10orf46 Lentiviral Activation Particles (h2) - sc-414517-LAC-2 from Santa Cruz Biotechnology
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C10orf46 siRNA (h) - sc-90590 from Santa Cruz Biotechnology
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C10orf46 shRNA Plasmid (h) - sc-90590-SH from Santa Cruz Biotechnology
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C10orf46 shRNA (h) Lentiviral Particles - sc-90590-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU093821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4157 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4157 from Sigma-Aldrich
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CACUL1 siRNA (Human) - CRJ5370 from Cohesion Biosciences
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CAC1 RNAi - H00143384-R01 from Novus Biologicals
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CACUL1 - MBS8225044 from MyBioSource
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shRNA set against Human C10orf46 (NM_153810.4) - SHH248706 from Creative biogene
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Human CACUL1 siRNA - orb275871 from Biorbyt
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CACUL1 shRNA Plasmid (Human) - CHJ5370 from Cohesion Biosciences
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CACUL1 miRNA 3'UTR clone - MiUTR1H-01006 from Creative biogene
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