Gene Symbol | HIST2H2BE |
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Entrez Gene | 8349 |
Alt Symbol | GL105, H2B, H2B.1, H2BFQ, H2BGL105, H2BQ |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 2, H2be |
Other Description | H2B histone family, member Q|histone 2, H2be|histone H2B type 2-E|histone H2B-GL105|histone H2B.q |
Swissprots | Q16778 Q4KMY1 A8K110 Q9UE88 Q5QNX0 A3KMC7 |
Accessions | AAN59961 CAA41051 CAI12568 EAW53605 Q16778 AK093747 AK289725 BAF82414 BC005827 AAH05827 BC069193 AAH69193 BC096121 AAH96121 BC098112 AAH98112 BC098289 AAH98289 BC107084 AAI07085 BC107085 AAI07086 CR541895 CAG46693 HQ447538 ADQ32024 M60756 AAA63192 NM_003528 NP_003519 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone H2B peptide - ab20338 from Abcam
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Human Histone H2B (di methyl K43) peptide - ab23555 from Abcam
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Human Histone H2B (di methyl K5) peptide - ab26342 from Abcam
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Human Histone H2B (glcnac S112) peptide - ab166685 from Abcam
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Human Histone H2B (glcnac S36) peptide - ab166688 from Abcam
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Human Histone H2B (hydroxy P1 + P3 + P8 + P10) peptide - ab17211 from Abcam
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Human Histone H2B (hydroxy P10) peptide - ab32105 from Abcam
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Human Histone H2B (mono methyl K5) peptide - ab13211 from Abcam
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Human Histone H2B full length protein - ab159996 from Abcam
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Human Histone H2B full length protein - ab92409 from Abcam
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Human Histone H2B full length protein - ab198637 from Abcam
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Human Histone H2B peptide - ab5489 from Abcam
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Human Histone H2B peptide - ab13214 from Abcam
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Human Histone H2B peptide - ab16101 from Abcam
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Human Histone H2B peptide - ab13212 from Abcam
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Human Histone H2B peptide - ab13336 from Abcam
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Human Histone H2B peptide - ab17212 from Abcam
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Human Histone H2B peptide - ab18507 from Abcam
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Human Histone H2B peptide - ab35791 from Abcam
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Human Histone H2B peptide - ab35793 from Abcam
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Human Histone H2B peptide - ab166686 from Abcam
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Human Histone H2B protein fragment - ab159997 from Abcam
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Human HIST2H2BE protein (Native) - orb139018 from Biorbyt
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Histone H2B type 2-E - H00008349-P01 from Acris Antibodies
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Histone H2B type 2-E - H00008349-Q01-10 from Acris Antibodies
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