| Gene Symbol | Trpc1 |
|---|---|
| Entrez Gene | 89821 |
| Alt Symbol | Trrp1 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | transient receptor potential cation channel, subfamily C, member 1 |
| Other Description | TRP-1|short transient receptor potential channel 1|transient receptor protein 1 |
| Swissprots | Q9QX01 |
| Accessions | Q9QX01 AF061266 AAC67387 AF061873 AAC16725 DQ839447 ABH07673 XM_008766568 XP_008764790 XM_008766569 XP_008764791 XM_008766570 XP_008764792 XM_008766571 XP_008764793 NM_053558 NP_446010 |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. |
| Subcellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in brain, hippocampus, amygdala, Purkinje cells and single neurons in the cortex and striatum. {ECO:0000269|PubMed:11301024}. |
| Top Pathways | Pancreatic secretion, Glutamatergic synapse |
TRPC1 siRNA (r) - sc-61872 from Santa Cruz Biotechnology
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TRPC1 shRNA Plasmid (r) - sc-61872-SH from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN64658 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND64658 from Sigma-Aldrich
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TRPC1 siRNA (Rat) - CRR2711 from Cohesion Biosciences
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TRPC1 - MBS8211890 from MyBioSource
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shRNA set against Rat TRPC1 (NM_053558.1) - SHH435532 from Creative biogene
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shRNA set against Rat Trpc1(NM_053558.1) - SHL096708 from Creative biogene
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Rat TRPC1 siRNA - orb297560 from Biorbyt
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TRPC1 shRNA Plasmid (Rat) - CHR2711 from Cohesion Biosciences
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TRPC1 miRNA 3'UTR clone - MiUTR1R-08221 from Creative biogene
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