| Gene Symbol |
Trpc1
|
| Entrez Gene |
89821
|
| Alt Symbol |
Trrp1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
transient receptor potential cation channel, subfamily C, member 1
|
| Other Description |
TRP-1|short transient receptor potential channel 1|transient receptor protein 1
|
| Swissprots |
Q9QX01
|
| Accessions |
Q9QX01 AF061266 AAC67387 AF061873 AAC16725 DQ839447 ABH07673 XM_008766568 XP_008764790 XM_008766569 XP_008764791 XM_008766570 XP_008764792 XM_008766571 XP_008764793 NM_053558 NP_446010
|
| Function |
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in brain, hippocampus, amygdala, Purkinje cells and single neurons in the cortex and striatum. {ECO:0000269|PubMed:11301024}.
|
| Top Pathways |
Pancreatic secretion, Glutamatergic synapse
|