Gene Symbol | LRRC4C |
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Entrez Gene | 57689 |
Alt Symbol | NGL-1, NGL1 |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 4C |
Other Description | leucine-rich repeat-containing protein 4C|netrin-G1 ligand |
Swissprots | Q7L0N3 A8K0T1 Q9HCJ2 |
Accessions | EAW68107 Q9HCJ2 AB046800 BAB13406 AI806109 AK289646 BAF82335 AY358293 AAQ88660 BC041374 AAH41374 BX951676 DA387604 DQ084201 AAY86708 DQ084202 AAY86709 XM_011520238 XP_011518540 XM_011520239 XP_011518541 XM_011520240 XP_011518542 XM_011520241 XP_011518543 XM_011520242 XP_011518544 XM_011520243 XP_011518545 XM_011520244 XP_011518546 XM_011520245 XP_011518547 NM_001258419 NP_001245348 NM_020929 NP_065980 NR_047673 NR_047674 |
Function | May promote neurite outgrowth of developing thalamic neurons. {ECO:0000269|PubMed:14595443}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:14595443, ECO:0000269|PubMed:21946559}; Single-pass type I membrane protein {ECO:0000269|PubMed:14595443, ECO:0000269|PubMed:21946559}. |
Tissue Specificity | Highly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show very weak or no expression. {ECO:0000269|PubMed:14595443}. |
Top Pathways | Axon guidance, Cell adhesion molecules (CAMs) |
Human Netrin G1 ligand full length protein - ab132385 from Abcam
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Human Netrin G1 ligand protein fragment - ab153462 from Abcam
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Mouse Netrin G1 ligand peptide - ab32779 from Abcam
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LRRC4C Antibody Blocking Peptide - LS-E5936 from LifeSpan Bioscience
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NGL-1/LRRC4C Recombinant Protein - H00057689-P01 from Novus Biologicals
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NGL-1/LRRC4C Partial Recombinant Protein - H00057689-Q01 from Novus Biologicals
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LRRC4C-Antibody-Center-Blocking-Peptide - BP18504c from Abgent, a WuXi AppTec company
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Recombinant Human NGL-1/LRRC4C, CF - 4899-NR-050 from R&D Systems
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LRRC4C Blocking Peptide - 33R-5546 from Fitzgerald
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LRRC4C / NGL1 - H00057689-P01-10 from Acris Antibodies
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LRRC4C / NGL1 - H00057689-P01-25 from Acris Antibodies
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LRRC4C / NGL1 - H00057689-Q01-10 from Acris Antibodies
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LRRC4C / NGL1 - H00057689-Q01-25 from Acris Antibodies
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LRRC4C fusion protein - Ag4811 from Proteintech Group
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LRRC4C fusion protein - ag5035 from Proteintech Group
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Recombinant Human LRRC4C, GST-tagged - LRRC4C-640H from Creative Biomart
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Recombinant Human LRRC4C, His-tagged - LRRC4C-733H from Creative Biomart
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Recombinant Human NGL-1/LRRC4C Protein, CF - 4899-NR from R&D Systems
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LRRC4C Peptide, Human - M34GP08914H from Creative Peptides
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NGL-1/LRRC4C Recombinant Protein Antigen - NBP2-49001PEP from Novus Biologicals
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NGL-1/LRRC4C Recombinant Protein Antigen - NBP2-58242PEP from Novus Biologicals
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Leucine-rich repeat-containing protein 4C (LRRC4C), Recombinant Protein - MBS7019165 from MyBioSource
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