Gene Symbol | CD40 |
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Entrez Gene | 958 |
Alt Symbol | Bp50, CDW40, TNFRSF5, p50 |
Species | Human |
Gene Type | protein-coding |
Description | CD40 molecule, TNF receptor superfamily member 5 |
Other Description | B cell surface antigen CD40|B cell-associated molecule|CD40 antigen (TNF receptor superfamily member 5)|CD40 type II isoform|CD40L receptor|nerve growth factor receptor-related B-lymphocyte activation molecule|tumor necrosis factor receptor superfamily member 5 |
Swissprots | Q5U007 E1P5S9 Q9BYU0 Q7M4Q8 Q5JY15 Q53GN5 P25942 Q86YK5 |
Accessions | AAR84238 ABI49511 ABK41937 CAJ00027 CAJ00028 CAJ00033 CAJ00034 CAJ00124 CAJ00125 CAJ00728 CAJ00729 CAL31951 CAL31952 CAL47757 CAL47758 CAL47760 CAL47761 CAL99221 CAL99222 CAL99226 CAL99227 CAQ64629 CAQ64630 CAX20923 CAX20924 CAZ64457 CAZ64458 CBJ55369 CBJ55370 CBL93995 CBX32768 CBX32769 CBX55113 CBX55114 CBX55116 CBX55117 CBX89251 CBX89252 CBY65289 CBY65290 CCA63957 CCA63958 CDH93531 CDH93532 EAW75757 EAW75758 EAW75759 EAW75760 EAW75761 EAW75762 EAW75763 P25942 AB209660 BAD92897 AJ300189 CAC29424 AK222896 BAD96616 AY225405 AAO43990 BC012419 AAH12419 BC064518 AAH64518 BM761221 BT019901 AAV38704 BX364284 BX364285 DQ891804 ABM82730 DQ894988 ABM85914 HY063089 HY088000 XM_005260617 XP_005260674 XM_005260619 XP_005260676 XM_011529109 XP_011527411 XR_936660 NM_001250 NP_001241 NM_001302753 NP_001289682 NM_152854 NP_690593 NR_126502 |
Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
Subcellular Location | Isoform I: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | B-cells and in primary carcinomas. |
Top Pathways | Toll-like receptor signaling pathway, Epstein-Barr virus infection, Cell adhesion molecules (CAMs), Asthma, HTLV-I infection |
CD40 protein (Fc Chimera Active) - ab83917 from Abcam
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Active human CD40 protein fragment - ab155710 from Abcam
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Human CD40 full length protein - ab134843 from Abcam
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Human CD40 protein fragment - ab151383 from Abcam
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Human CD40 protein fragment - ab186982 from Abcam
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CD40 Antibody Blocking Peptide - LS-E5374 from LifeSpan Bioscience
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CD40 Antibody Blocking Peptide - LS-E15435 from LifeSpan Bioscience
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CD40 Antibody Blocking Peptide - LS-E15436 from LifeSpan Bioscience
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CD40/TNFRSF5 Recombinant Protein - H00000958-P01 from Novus Biologicals
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CD40/TNFRSF5 Recombinant Protein - H00000958-P02 from Novus Biologicals
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CD40/TNFRSF5 Recombinant Protein - H00000958-P03 from Novus Biologicals
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CD40/TNFRSF5 Recombinant Protein - H00000958-G01 from Novus Biologicals
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CD40-Antibody-C-term-Blocking-Peptide - BP17871b from Abgent, a WuXi AppTec company
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Recombinant Human CD40/TNFRSF5 Fc Chimera, CF - 1493-CD-050 from R&D Systems
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Recombinant Rat CD40/TNFRSF5 Fc Chimera, CF - 8229-CD-050 from R&D Systems
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CD40 Protein Lysate (APL10756) - APL10756 from Aviva Systems Biology
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Cynomolgus CD40 protein (His Tag) - orb138439 from Biorbyt
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Human CD40 (Fc Tag) protein - orb232247 from Biorbyt
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Human CD40 His tag protein - orb83393 from Biorbyt
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Human CD40 Fc His tag protein - orb82902 from Biorbyt
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Human CD40 protein - orb49279 from Biorbyt
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Cynomolgus CD40 protein - orb138438 from Biorbyt
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Human CD40 protein - orb180218 from Biorbyt
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CD40 Blocking Peptide - 33R-8706 from Fitzgerald
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CD40 Blocking Peptide - 33R-9985 from Fitzgerald
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