Gene Symbol | BECN1 |
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Entrez Gene | 527278 |
Alt Symbol | ATG6 |
Species | Bovine |
Gene Type | protein-coding |
Description | beclin 1, autophagy related |
Other Description | beclin-1|coiled-coil myosin-like BCL2-interacting protein |
Swissprots | Q4A1L4 |
Accessions | DAA18463 Q4A1L4 AM051355 CAJ19744 BC102177 AAI02178 XM_010816250 XP_010814552 NM_001033627 NP_001028799 |
Function | Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense (By similarity). {ECO:0000250|UniProtKB:Q14457}. |
Subcellular Location | Cytoplasm {ECO:0000250|UniProtKB:O88597}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q14457}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q14457}. Endosome membrane {ECO:0000250|UniProtKB:Q14457}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q14457}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q14457}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q14457}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q14457}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q14457}. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells. {ECO:0000250|UniProtKB:O88597, ECO:0000250|UniProtKB:Q14457}. |
Top Pathways | Regulation of autophagy |
Recombinant Bovine Beclin-1(BECN1) - CSB-YP671073BO CSB-EP671073BO CSB-BP671073BO CSB-MP671073BO from Cusabio
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Beclin-1 (BECN1), Recombinant Protein - MBS1450122 from MyBioSource
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