Gene Symbol | Hyal2 |
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Entrez Gene | 15587 |
Alt Symbol | AI256841, AU020858, AW555733 |
Species | Mouse |
Gene Type | protein-coding |
Description | hyaluronoglucosaminidase 2 |
Other Description | hyal-2|hyaluronidase 2|hyaluronidase-2|hyaluronoglucosaminidase-2 |
Swissprots | Q99MT0 Q99MS9 O35631 O35632 |
Accessions | CAA03889 EDL21201 EDL21202 O35632 AF302843 AAK28481 AF302844 AAK28482 AF422177 AAL17823 AF535140 AAO49503 AJ000059 CAA03888 AK080146 AK087358 BAC39851 AK088806 BAC40583 AK133886 BAE21913 BC060047 XM_006511643 XP_006511706 XM_006511644 XP_006511707 XM_006511645 XP_006511708 NM_010489 NP_034619 |
Function | Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
Tissue Specificity | Widely expressed. In the brain, expressed during embryonic stages but expression decreases after birth and is barely detectable in adult brain. {ECO:0000269|PubMed:9790770}. |
Top Pathways | Glycosaminoglycan degradation |
Mouse HYAL2 Protein - abx067147 from Abbexa
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Hyaluronoglucosaminidase 2 (HYAL2), Mouse - 20-8902 from ARP American Research Products
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Recombinant Hyaluronoglucosaminidase 2 (HYAL2) - RPE237Mu01 from Cloud-clone
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Recombinant Mouse Hyaluronidase-2(Hyal2) - CSB-YP010919MO CSB-EP010919MO CSB-BP010919MO CSB-MP010919MO from Cusabio
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Hyaluronoglucosaminidase 2 (HYAL2) - RPU141951 from Biomatik
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Recombinant Mouse HYAL2 Protein - HYAL2-7953M from Creative Biomart
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Recombinant Hyaluronoglucosaminidase 2 (HYAL2) - RPU41951 from Biomatik
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HYAL2 Recombinant Protein (OPCD04062) - OPCD04062 from Aviva Systems Biology
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Hyaluronidase-2 (Hyal2), Recombinant Protein - MBS1109475 from MyBioSource
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Hyaluronoglucosaminidase 2 (HYAL2), Recombinant Protein - MBS2010567 from MyBioSource
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