| Gene Symbol |
Hyal2
|
| Entrez Gene |
15587
|
| Alt Symbol |
AI256841, AU020858, AW555733
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
hyaluronoglucosaminidase 2
|
| Other Description |
hyal-2|hyaluronidase 2|hyaluronidase-2|hyaluronoglucosaminidase-2
|
| Swissprots |
Q99MT0 Q99MS9 O35631 O35632
|
| Accessions |
CAA03889 EDL21201 EDL21202 O35632 AF302843 AAK28481 AF302844 AAK28482 AF422177 AAL17823 AF535140 AAO49503 AJ000059 CAA03888 AK080146 AK087358 BAC39851 AK088806 BAC40583 AK133886 BAE21913 BC060047 XM_006511643 XP_006511706 XM_006511644 XP_006511707 XM_006511645 XP_006511708 NM_010489 NP_034619
|
| Function |
Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. In the brain, expressed during embryonic stages but expression decreases after birth and is barely detectable in adult brain. {ECO:0000269|PubMed:9790770}.
|
| Top Pathways |
Glycosaminoglycan degradation
|