Gene Symbol | C1QC |
---|---|
Entrez Gene | 714 |
Alt Symbol | C1Q-C, C1QG |
Species | Human |
Gene Type | protein-coding |
Description | complement component 1, q subcomponent, C chain |
Other Description | complement C1q subcomponent subunit C|complement component 1, q subcomponent, gamma polypeptide |
Swissprots | Q96H05 Q7Z502 P02747 Q96DL2 |
Accessions | EAW95016 EAW95017 EAW95018 P02747 AF087892 AAP97191 AK057792 BAB71575 AK130613 AK226152 AM392881 CAL37759 AM393232 CAL38110 AM393519 CAL38396 BC009016 AAH09016 BG060138 CB995661 DA849505 NM_001114101 NP_001107573 NM_172369 NP_758957 |
Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection |
C1q-C (A-12) - sc-365301 from Santa Cruz Biotechnology
|
||||||||||
C1q-C (H-55) - sc-28187 from Santa Cruz Biotechnology
|
||||||||||
C1q-C (P-20) - sc-27669 from Santa Cruz Biotechnology
|
||||||||||
C1q-C (C-20) - sc-27668 from Santa Cruz Biotechnology
|
||||||||||
Anti-C1QC antibody - ab92689 from Abcam
|
||||||||||
Anti-C1QC antibody [EPR2984Y] - ab75756 from Abcam
|
||||||||||
Anti-C1QG antibody - ab103550 from Abcam
|
||||||||||
Anti-C1QG antibody [EPR2983] - ab76491 from Abcam
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (Internal, clone EPR2984Y) - LS-C105453 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa81-130) - LS-C119868 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (Gln119) - LS-C177814 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (Internal, clone EPR2983) - LS-C105528 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa93-120) - LS-C168048 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa100-128, APC) - LS-C208160 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa100-128, AP) - LS-C208159 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa100-128, Biotin) - LS-C208161 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa100-128, FITC) - LS-C208162 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa100-128, PE) - LS-C208164 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa100-128, Azide-free, HRP) - LS-C208163 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody - LS-C309651 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody - LS-C309652 from LifeSpan Bioscience
|
||||||||||
Anti-C1QG / Complement C1QC Antibody (aa100-128) - LS-C329283 from LifeSpan Bioscience
|
||||||||||
Complement Component C1qC Antibody - NBP2-30024 from Novus Biologicals
|
||||||||||
Complement Component C1qC Antibody [Unconjugated] - AF3337 from Novus Biologicals
|
||||||||||
Complement Component C1qC Antibody - NBP1-51346 from Novus Biologicals
|