COPB1

Gene Symbol	COPB1
Entrez Gene	1315
Alt Symbol	COPB
Species	Human
Gene Type	protein-coding
Description	coatomer protein complex, subunit beta 1
Other Description	beta coat protein|beta-coat protein|beta-cop|coatomer subunit beta
Swissprots	Q9NTK2 P53618 Q6GTT7 Q9UNW7 D3DQX0
Accessions	EAW68481 EAW68482 EAW68483 EAW68484 EAW68485 P53618 AA443270 AF084457 AAD41240 AF111807 AAL39009 AK001203 AK128844 AL136593 CAB66528 AM393381 CAL38259 BC012572 BC037280 AAH37280 DA725605 DB455108 DQ892479 ABM83405 DQ895690 ABM86616 X82103 CAA57622 NM_001144061 NP_001137533 NM_001144062 NP_001137534 NM_016451 NP_057535
Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Plays a functional role in facilitating the transport of kappa- type opioid receptor mRNAs into axons and enhances translation of these proteins. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipi
Subcellular Location	Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane. Endoplasmic reticulum- Golgi intermediate compartment. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Proteolytic cleavage by CAPN8 triggers translocation from Golgi to cytoplasm (By similarity). Found in perinuclear vesicular-tubular clusters (VTCs) and in the Golgi region where associated with vesicles, buds and rims of the Golgi stack (By similarity). Occasionally present at the trans-side of Golgi, but mainly present at the cis- Golgi side in transitional areas (TA), on so-called peripheral elements (PE) consisting of tubules and vesicles located between the cup-shaped transitional elements (TE) of the rough endoplasmic reticulum (RER) and the cis-most Golgi cisternae (By similarity). Present in cy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat beta COP peptide - ab26329 from Abcam Category Peptide

COPB2 / Beta-COP Antibody Blocking Peptide - LS-E6251 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COPB1 / Beta-COP Antibody Blocking Peptide - LS-E2800 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COPB1 / Beta-COP Antibody Blocking Peptide - LS-E18830 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human beta COP Protein - H00001315-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

COPB1-Antibody-Center-Blocking-peptide - BP13904c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

COPB1 Blocking Peptide - 33R-7619 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Coatomer subunit beta (COPB) - H00001315-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Coatomer subunit beta (COPB) - H00001315-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human COPB1, His-tagged - COPB1-27477TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Coatomer subunit beta(COPB1) ,partial - CSB-YP005783HU CSB-EP005783HU CSB-BP005783HU CSB-MP005783HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Coatomer subunit beta (COPB) (transcript variant 1) - TP306009 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Coatomer subunit beta (COPB) (transcript variant 2) - TP327856 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

beta COP Recombinant Protein Antigen - NBP2-38519PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

beta COP Recombinant Protein Antigen - NBP2-39027PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

COPB1 Peptide, Human - M34GP03494H from Creative Peptides Category Peptide Source Synthetic. Species Human

COPB1 fusion protein - Ag26518 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

COPB1 fusion protein - Ag26545 from Proteintech Group Category Protein Source E. coli -derived, PET30a Species Human

Coatomer subunit beta (COPB1), partial, Recombinant Protein - MBS964081 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more