NFE2

Gene Symbol	NFE2
Entrez Gene	4778
Alt Symbol	NF-E2, p45
Species	Human
Gene Type	protein-coding
Description	nuclear factor, erythroid 2
Other Description	leucine zipper protein NF-E2|nuclear factor (erythroid-derived 2), 45kD|nuclear factor (erythroid-derived 2), 45kDa|nuclear factor, erythroid-derived 2 45 kDa subunit|p45 NF-E2|transcription factor NF-E2 45 kDa subunit
Swissprots	Q6ICV9 Q16621 Q07720
Accessions	ABC79302 CCQ43105 CCQ77681 EAW96771 EAW96772 EAW96773 Q16621 AK290555 BAF83244 AK290564 BAF83253 AK313207 BAG36023 BC005044 AAH05044 BE243330 BT007288 AAP35952 BX406317 CR450284 CAG29280 DQ893437 ABM84363 DQ896796 ABM87795 EU176417 ABW03868 GD141614 GU068583 ACY92458 L13974 AAA35612 L24122 AAA16118 S77763 AAB34115 XM_005268906 XP_005268963 XM_011538397 XP_011536699 NM_001136023 NP_001129495 NM_001261461 NP_001248390 NM_006163 NP_006154
Function	Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. {ECO:0000269|PubMed:11154691, ECO:0000269|PubMed:16287851}.
Subcellular Location	Nucleus, PML body. Cytoplasm. Note=The sumoylated form locates to the nuclear bodies PML oncogenic domains (PODs). Translocated to the cytoplasm through interaction with ITCH.
Tissue Specificity	Expressed in hematopoietic cells and also in colon and testis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Nuclear Factor Erythroid Derived 2 full length protein - ab117042 from Abcam Category Protein Source Wheat germ Species Human

Human Nuclear Factor Erythroid Derived 2 full length protein - ab169899 from Abcam Category Protein Source E. coli Species Human

Human Nuclear Factor Erythroid Derived 2 protein fragment - ab158991 from Abcam Category Protein Source Wheat germ Species Human

NFE2 / p45 Antibody Blocking Peptide - LS-E2527 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFE2 / p45 Antibody Blocking Peptide - LS-E10883 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFE2 / p45 Antibody Blocking Peptide - LS-E21235 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Nuclear Factor Erythroid Derived 2 Protein - H00004778-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Nuclear Factor Erythroid Derived 2 Protein - H00004778-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NFE2-Antibody-C-term-Blocking-peptide - BP13561b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NFE2 - H00004778-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NFE2 - H00004778-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NFE2 - H00004778-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NFE2 - H00004778-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NFE2 fusion protein - Ag1570 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NFE2 - NFE2-28428TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human NFE2, GST-tagged - NFE2-1276H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Transcription factor NF-E2 45 kDa subunit(NFE2) - CSB-YP618088HU CSB-EP618088HU CSB-BP618088HU CSB-MP618088HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NFE2 - TP302924 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Nuclear Factor Erythroid Derived 2 Recombinant Protein Antigen - NBP1-82580PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NFE2 Peptide, Human - M34GP10332H from Creative Peptides Category Peptide Source Synthetic. Species Human

p45, Recombinant Protein - MBS140912 from MyBioSource Category Protein Prices $140.00, $205.00, $3,515.00 Sizes 5 µg, 20 µg, 1 mg Source Sf9 Insect Cells

Protein nfe2 (nfe2), Recombinant Protein - MBS1453312 from MyBioSource Category Protein Prices $1,070.00, $1,070.00, $1,300.00, $1,300.00, $1,675.00, $1,675.00, $2,140.00, $2,140.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rhizobium

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