Gene Symbol | SELE |
---|---|
Entrez Gene | 6401 |
Alt Symbol | CD62E, ELAM, ELAM1, ESEL, LECAM2 |
Species | Human |
Gene Type | protein-coding |
Description | selectin E |
Other Description | CD62 antigen-like family member E|E-selectin|ELAM-1|endothelial adhesion molecule 1|endothelial leukocyte adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2|leukocyte-endothelial cell adhesion molecule 2 |
Swissprots | P16111 A2RRD6 P16581 |
Accessions | AAA52375 AAN01237 EAW90860 P16581 AK314214 BAG36888 AY367062 AAQ67702 BC131551 AAI31552 BC142677 AAI42678 BC142711 AAI42712 DB209354 M24736 AAA52376 M30640 AAA52377 NM_000450 NP_000441 |
Function | Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis. {ECO:0000269|PubMed:1689848}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cell adhesion molecules (CAMs), Malaria, African trypanosomiasis, TNF signaling pathway |