| Gene Symbol |
SPCS3
|
| Entrez Gene |
60559
|
| Alt Symbol |
PRO3567, SPC22/23, SPC3, YLR066W
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
signal peptidase complex subunit 3 homolog (S. cerevisiae)
|
| Other Description |
SPase 22 kDa subunit|SPase 22/23 kDa subunit|microsomal signal peptidase 22/23 kDa subunit|microsomal signal peptidase 23 kDa subunit|signal peptidase complex subunit 3
|
| Swissprots |
P61009
|
| Accessions |
CAH05566 EAX04718 EAX04719 P61009 AK026302 BAB15437 AK092634 AL136660 CAB66595 AY359044 AAQ89403 BC043490 BC047290 AAH47290 BC053883 DB285025 EU831652 ACE87252 EU831735 ACE86569 HQ448610 ADQ33088 NM_021928 NP_068747
|
| Function |
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
|
| Subcellular Location |
Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Top Pathways |
Protein export
|
![Western Blot: SPCS3 Overexpression Lysate (Adult Normal) [NBL1-16389] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SPCS3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7234_SPCS3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16389-img0002.jpg)