Gene Symbol | SERPINA9 |
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Entrez Gene | 327657 |
Alt Symbol | GCET1, SERPINA11, SERPINA11b |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 |
Other Description | centerin|germinal center B-cell-expressed transcript 1 protein|serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9|serine proteinase inhibitor A11|serpin A9 |
Swissprots | Q86YP7 B9ZVX3 Q86WD6 Q86WD7 Q6UWP9 Q2T9J2 Q86YP6 B4DVH4 Q86WD4 Q86WD5 |
Accessions | EAW81577 Q86WD7 AK301082 BAG62686 AY185496 AAO32345 AY185497 AAO32346 AY220118 AAO65242 AY220119 AAO65243 AY220120 AAO65244 AY220121 AAO65245 AY358700 AAQ89063 BC089422 BC111498 AAI11499 XM_011536713 XP_011535015 XM_011536714 XP_011535016 XM_011536715 XP_011535017 XM_011536716 XP_011535018 XM_011536717 XP_011535019 NM_001042518 NP_001035983 NM_001284275 NP_001271204 NM_001284276 NP_001271205 NM_175739 NP_783866 |
Function | Protease inhibitor that inhibits trypsin and trypsin- like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro). {ECO:0000269|PubMed:17447896}. |
Subcellular Location | Isoform 7: Membrane {ECO:0000305}; Single- pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies. {ECO:0000269|PubMed:12819018, ECO:0000269|PubMed:17447896, ECO:0000269|PubMed:17898315, ECO:0000269|PubMed:18550480}. |
GCET1 CRISPR/Cas9 KO Plasmid (h) - sc-415475 from Santa Cruz Biotechnology
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GCET1 HDR Plasmid (h) - sc-415475-HDR from Santa Cruz Biotechnology
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GCET1 Double Nickase Plasmid (h) - sc-415475-NIC from Santa Cruz Biotechnology
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GCET1 Double Nickase Plasmid (h2) - sc-415475-NIC-2 from Santa Cruz Biotechnology
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GCET1 CRISPR Activation Plasmid (h) - sc-415475-ACT from Santa Cruz Biotechnology
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GCET1 CRISPR Activation Plasmid (h2) - sc-415475-ACT-2 from Santa Cruz Biotechnology
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GCET1 Lentiviral Activation Particles (h) - sc-415475-LAC from Santa Cruz Biotechnology
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GCET1 Lentiviral Activation Particles (h2) - sc-415475-LAC-2 from Santa Cruz Biotechnology
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SerpinA9 siRNA (h) - sc-92169 from Santa Cruz Biotechnology
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SerpinA9 shRNA Plasmid (h) - sc-92169-SH from Santa Cruz Biotechnology
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SerpinA9 shRNA (h) Lentiviral Particles - sc-92169-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU071831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19136 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19136 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02919 from Sigma-Aldrich
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SERPINA9 siRNA (Human) - CRJ7202 from Cohesion Biosciences
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SERPINA9 - MBS8224454 from MyBioSource
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shRNA set against Human SERPINA9 (NM_175739.3) - SHH405072 from Creative biogene
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shRNA set against Human SERPINA9(NM_001042518.1) - SHR216438 from Creative biogene
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shRNA set against Human SERPINA9(NM_175739.3) - SHR216498 from Creative biogene
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Human SERPINA9 siRNA - orb277703 from Biorbyt
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SERPINA9 shRNA Plasmid (Human) - CHJ7202 from Cohesion Biosciences
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SERPINA9 miRNA 3'UTR clone - MiUTR1H-09297 from Creative biogene
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SERPINA9 miRNA 3'UTR clone - MiUTR1H-09298 from Creative biogene
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