| Gene Symbol |
SERPINA9
|
| Entrez Gene |
327657
|
| Alt Symbol |
GCET1, SERPINA11, SERPINA11b
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
|
| Other Description |
centerin|germinal center B-cell-expressed transcript 1 protein|serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9|serine proteinase inhibitor A11|serpin A9
|
| Swissprots |
Q86YP7 B9ZVX3 Q86WD6 Q86WD7 Q6UWP9 Q2T9J2 Q86YP6 B4DVH4 Q86WD4 Q86WD5
|
| Accessions |
EAW81577 Q86WD7 AK301082 BAG62686 AY185496 AAO32345 AY185497 AAO32346 AY220118 AAO65242 AY220119 AAO65243 AY220120 AAO65244 AY220121 AAO65245 AY358700 AAQ89063 BC089422 BC111498 AAI11499 XM_011536713 XP_011535015 XM_011536714 XP_011535016 XM_011536715 XP_011535017 XM_011536716 XP_011535018 XM_011536717 XP_011535019 NM_001042518 NP_001035983 NM_001284275 NP_001271204 NM_001284276 NP_001271205 NM_175739 NP_783866
|
| Function |
Protease inhibitor that inhibits trypsin and trypsin- like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro). {ECO:0000269|PubMed:17447896}.
|
| Subcellular Location |
Isoform 7: Membrane {ECO:0000305}; Single- pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies. {ECO:0000269|PubMed:12819018, ECO:0000269|PubMed:17447896, ECO:0000269|PubMed:17898315, ECO:0000269|PubMed:18550480}.
|